Relative Activity Factor (RAF)-Based Scaling of Uptake Clearance Mediated by Organic Anion Transporting Polypeptide (OATP) 1B1 and OATP1B3 in Human Hepatocytes.
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DOI: 10.1021/acs.molpharmaceut.0c00025
Abstract: respectively). As shown in Table 1, the correct RAF1B1 and RAF1B3 values for lot OJE were 3.65 and 0.627, respectively, which provided the CLuptake,1B1+1B3,RAF values in the amended Table 3 shown herein. By using the… read more here.
Keywords: clearance mediated; lot oje; raf; raf based ... See more keywords