Thermoresponsive and acid-cleavable amphiphilic copolymer micelles for controlled drug delivery
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DOI: 10.1080/00914037.2017.1291514
Abstract: ABSTRACT Thermoresponsive and acid-cleavable amphiphilic block copolymers poly(N-isopropylacrylamide)-acetal-poly(4-substituted-ε-caprolactones) (PNiPAAm-a-PXCLs) containing an acidic-cleavable acetal linkage at the junction between the temperature-sensitive hydrophilic PNiPAAm and the degradable hydrophobic block PXCL were synthesized through ring-opening polymerization and electrophilic… read more here.
Keywords: cleavable amphiphilic; copolymer micelles; thermoresponsive acid; amphiphilic copolymer ... See more keywords