IRE1α nucleotide sequence cleavage specificity in the unfolded protein response
Sign Up to like & getrecommendations! Published in 2017 at "FEBS Letters"
DOI: 10.1002/1873-3468.12546
Abstract: Inositol‐requiring enzyme 1 (IRE1) is a conserved sensor of the unfolded protein response that has protein kinase and endoribonuclease (RNase) enzymatic activities and thereby initiates HAC1/XBP1 splicing. Previous studies demonstrated that human IRE1α (hIRE1α) does… read more here.
Keywords: cleavage; unfolded protein; protein response; cleavage specificity ... See more keywords
Mitochondrial ferritin expression in human macrophages is facilitated by thrombin‐mediated cleavage under hypoxia
Sign Up to like & getrecommendations! Published in 2022 at "FEBS Letters"
DOI: 10.1002/1873-3468.14545
Abstract: Ferritins are iron storage proteins, which maintain cellular iron homeostasis. Among these proteins, the ferritin heavy chain is well characterized, but the regulatory principles of mitochondrial ferritin (FTMT) remain elusive. FTMT appears to be cleaved… read more here.
Keywords: cleavage; mitochondrial ferritin; expression; hypoxia ... See more keywords
Paclitaxel induces apoptosis through the TAK1–JNK activation pathway
Sign Up to like & getrecommendations! Published in 2020 at "FEBS Open Bio"
DOI: 10.1002/2211-5463.12917
Abstract: Paclitaxel (PTX) has previously been used to treat tumours of various tissue origins, such as lung, breast, ovarian, prostate cancers and leukemia. PTX‐induced apoptosis is associated with p38 mitogen‐activated protein kinase (p38 MAPK), extracellular signal‐regulated… read more here.
Keywords: apoptosis; jnk; cleavage; tak1 ... See more keywords
Simultaneous Oxidative Cleavage of Lignin and Reduction of Furfural via Efficient Electrocatalysis by P‐Doped CoMoO4
Sign Up to like & getrecommendations! Published in 2023 at "Advanced Materials"
DOI: 10.1002/adma.202208284
Abstract: Electrochemical oxidative lignin cleavage and coupled 2‐furaldehyde reduction provide a promising approach for producing high‐value added products. However, developing efficient bifunctional electrocatalysts with noble‐metal‐like activity still remains a challenge. Here, an efficient electrochemical strategy is… read more here.
Keywords: lignin; cleavage; oxidative cleavage; simultaneous oxidative ... See more keywords
Cleavage of an RNA Model Compound by an Arylmercury Complex
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DOI: 10.1002/cbic.202000799
Abstract: A water‐soluble arylmercury complex has been synthesized, and its ability to catalyze the cleavage of the phosphodiester linkage of the RNA model compound adenylyl‐3′,5′‐(2′,3′‐O‐methyleneadenosine) has been assessed over a pH range of 3–8.5 and a… read more here.
Keywords: arylmercury complex; cleavage; model compound; rna model ... See more keywords
Heterogeneous Cobalt‐Catalyzed C−C Bond Cleavage in Alcohols to Carbonyl Compounds
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DOI: 10.1002/cctc.202100950
Abstract: Cobalt oxide hydrate (Co(OH)x) supported on metal oxides were prepared. The oxidative cleavage of C(OH)−C bond in alcohol was catalyzed by Co(OH)x/metal oxides using molecular oxygen as the oxidant, and the corresponding product was obtained… read more here.
Keywords: cleavage; bond; heterogeneous cobalt; cobalt catalyzed ... See more keywords
Two Heads are Better than One：Weak Bonds Joint Effects Catalyze the Cleavage of Strong C-C Bond of Lignin-Inspired Compounds and Lignin in Air by Ionic Liquids.
Sign Up to like & getrecommendations! Published in 2020 at "ChemSusChem"
DOI: 10.1002/cssc.202001828
Abstract: Oxidation of lignin through selective C-C bond cleavage via metal-free and mild strategies is promising but challenging to value-added aromatics. We discovered that cation of ionic liquids (ILs) could effectively catalyze this kind of strong… read more here.
Keywords: weak bonds; cleavage; lignin; bond ... See more keywords
Photocatalytic cleavage of C(sp3)-N bond in trialkylamines to dialkylamines and olefins.
Sign Up to like & getrecommendations! Published in 2022 at "ChemSusChem"
DOI: 10.1002/cssc.202201119
Abstract: Development of new and green strategy for C(sp 3 )-N bond cleavage is very interesting. Herein, we report the work for photocatalytic cleavage of C(sp 3 )-N bond of trialkylamines, in concurrent with formation of… read more here.
Keywords: cleavage; photocatalytic cleavage; cleavage sp3; dialkylamines olefins ... See more keywords
Malt1 self‐cleavage is critical for regulatory T cell homeostasis and anti‐tumor immunity in mice
Sign Up to like & getrecommendations! Published in 2018 at "European Journal of Immunology"
DOI: 10.1002/eji.201847597
Abstract: Mucosa‐associated lymphoid tissue 1 (Malt1) regulates immune cell function by mediating the activation of nuclear factor κB (NF‐κB) signaling through both its adaptor and proteolytic function. Malt1 is also a target of its own protease… read more here.
Keywords: cleavage; anti tumor; malt1 self; self cleavage ... See more keywords
NLRP3 inflammasome triggers interleukin‐37 release from human monocytes
Sign Up to like & getrecommendations! Published in 2022 at "European Journal of Immunology"
DOI: 10.1002/eji.202149724
Abstract: IL‐37 is an anti‐inflammatory member of the IL‐1 family that dampens inflammation associated with many noncommunicable diseases. However, mechanisms of IL‐37 regulation remain understudied. We aimed to investigate the enzymatic cleavage of IL‐37 that potentiates… read more here.
Keywords: cleavage; inflammasome triggers; secretion; release ... See more keywords
Developing a capillary electrophoresis based method for dynamically monitoring enzyme cleavage activity using quantum dots‐peptide assembly
Sign Up to like & getrecommendations! Published in 2017 at "ELECTROPHORESIS"
DOI: 10.1002/elps.201700117
Abstract: Herein, a novel assay has been developed for monitoring PreScission protease (His‐PSP) mediated enzyme cleavage of ATTO 590 labeled peptide substrate (ATTO‐LEV). This novel method is based on combining the use of capillary electrophoresis and… read more here.
Keywords: enzyme cleavage; capillary electrophoresis; cleavage; method ... See more keywords