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Published in 2018 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.7b11582
Abstract: Most of the reported mitochondria-targeting molecules are lipophilic and cationic, and thus they may become cytotoxic with accumulation. Here we show enzymatic cleavage of branched peptides that carry negative charges for targeting mitochondria. Conjugating a…
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Keywords:
branched peptides;
peptides targeting;
cleavage branched;
targeting mitochondria ... See more keywords