Reductive Cleavage of C(sp2)-CF3 Bonds in Trifluoromethylpyridines.
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DOI: 10.1021/acs.orglett.3c00258
Abstract: A reductive detrifluoromethylation protocol has been developed making use of an earth-abundant alkoxide base and silicon hydride species. A variety of pyridine and quinoline substrates bearing alkyl, aryl, and amino functional groups are reduced in… read more here.
Keywords: cleavage sp2; sp2 cf3; cf3 bonds; sp2 ... See more keywords