IRE1α nucleotide sequence cleavage specificity in the unfolded protein response
Sign Up to like & getrecommendations! Published in 2017 at "FEBS Letters"
DOI: 10.1002/1873-3468.12546
Abstract: Inositol‐requiring enzyme 1 (IRE1) is a conserved sensor of the unfolded protein response that has protein kinase and endoribonuclease (RNase) enzymatic activities and thereby initiates HAC1/XBP1 splicing. Previous studies demonstrated that human IRE1α (hIRE1α) does… read more here.
Keywords: cleavage; unfolded protein; protein response; cleavage specificity ... See more keywords
In vivo cleavage specificity of Trypanosoma brucei editosome endonucleases
Sign Up to like & getrecommendations! Published in 2017 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkx116
Abstract: Abstract RNA editing is an essential post-transcriptional process that creates functional mitochondrial mRNAs in Kinetoplastids. Multiprotein editosomes catalyze pre-mRNA cleavage, uridine (U) insertion or deletion, and ligation as specified by guide RNAs. Three functionally and… read more here.
Keywords: cleavage; specificity trypanosoma; trypanosoma brucei; vivo cleavage ... See more keywords
Characterization of Legumain Degradome Confirms Narrow Cleavage Specificity.
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DOI: 10.17344/acsi.2018.4632
Abstract: Legumain or asparagine endopeptidase is a unique cysteine endopeptidase with a distinctive specificity for the hydrolysis of peptide bonds after asparagine and to a lesser extent after aspartate. It is ubiquitously expressed in various tissues… read more here.
Keywords: cleavage; narrow cleavage; specificity; characterization legumain ... See more keywords
Extended Cleavage Specificity of Human Neutrophil Elastase, Human Proteinase 3, and Their Distant Ortholog Clawed Frog PR3—Three Elastases With Similar Primary but Different Extended Specificities and Stability
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2018.02387
Abstract: Serine proteases are major granule constituents of several of the human hematopoietic cell lineages. Four proteolytically active such proteases have been identified in human neutrophils: cathepsin G (hCG), N-elastase (hNE), proteinase 3 (hPR-3), and neutrophil… read more here.
Keywords: elastase; hpr; extended cleavage; cleavage specificity ... See more keywords