Renoprotective effect of vinpocetine against ischemia/reperfusion injury: Modulation of NADPH oxidase/Nrf2, IKKβ/NF‐κB p65, and cleaved caspase‐3 expressions
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.23046
Abstract: Ischemia/reperfusion injury (IRI) during kidney transplantation is a serious clinical problem with a high mortality rate and a lack of therapy. Therefore, there is a need to improve the ability of the kidney to tolerate… read more here.
Keywords: ikk p65; effect vinpocetine; nadph oxidase; vinpocetine ... See more keywords
Chinese medicine CGA formula ameliorates liver fibrosis induced by carbon tetrachloride involving inhibition of hepatic apoptosis in rats.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of ethnopharmacology"
DOI: 10.1016/j.jep.2018.11.027
Abstract: ETHNOPHARMACOLOGICAL REVELVANCE CGA consisting of Cordyceps sinensis mycelia polysaccharide, gypenosides and amygdalin, was demonstrated to be the effective components formula in Fuzheng Huayu (FZHY) capsule, a traditional Chinese medicine approved by China food and drug… read more here.
Keywords: medicine; liver fibrosis; caspase cleaved; hepatic apoptosis ... See more keywords
Differential variations of autophagy and apoptosis in permanent focal cerebral ischaemia rat model
Sign Up to like & getrecommendations! Published in 2017 at "Brain Injury"
DOI: 10.1080/02699052.2017.1298005
Abstract: ABSTRACT Objective: Autophagy and apoptosis coexist in stroke, but the relationship between effects and complex is poorly understood. Herein, we investigated dynamic changes of autophagy and apoptosis at the penumbra in permanent cerebral ischaemia. Methods:… read more here.
Keywords: autophagy apoptosis; cerebral ischaemia; apoptosis; rat ... See more keywords
The Impact of Catalpol on Proliferation, Apoptosis, Migration, and Oxidative Stress of Lung Cancer Cells Based on Nrf2/ARE Signaling
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DOI: 10.1155/2022/5621341
Abstract: The effects of catalpol on lung cancer cell proliferation, apoptosis, migration, and oxidative stress via the Nrf2/ARE signaling pathway are investigated in this work. Catalpol-12 g/mL group, catalpol-24 g/mL group, catalpol-48 g/mL group, catalpol − 48 g/mL + vector group,… read more here.
Keywords: lung cancer; cancer; group; migration ... See more keywords
Transient Receptor Potential Channel, Vanilloid 5, Induces Chondrocyte Apoptosis in a Rat Osteoarthritis Model Through the Mediation of Ca2+ Influx
Sign Up to like & getrecommendations! Published in 2018 at "Cellular Physiology and Biochemistry"
DOI: 10.1159/000488725
Abstract: Background/Aims: Chondrocyte apoptosis is the most common pathological feature in cartilage in osteoarthritis (OA). Transient receptor potential channel vanilloid 5 (TRPV5) is important in regulating calcium ion (Ca2+) influx. Accumulating evidences suggest that Ca2+ is… read more here.
Keywords: chondrocyte apoptosis; trpv5; ca2; ca2 influx ... See more keywords
Histologic evaluation of Ki-67 and cleaved caspase-3 expression in feline mammary carcinoma
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Feline Medicine and Surgery"
DOI: 10.1177/1098612x16634150
Abstract: Objectives The purpose of this study was to evaluate histopathologic aspects of, and the expression of Ki-67 and cleaved caspase-3 in, feline mammary carcinoma (FMC). Methods Feline mammary tumors were surgically obtained by mastectomy from… read more here.
Keywords: caspase expression; mammary carcinoma; feline mammary; cleaved caspase ... See more keywords
Gross saponin of Tribulus terrestris improves erectile dysfunction in type 2 diabetic rats by repairing the endothelial function of the penile corpus cavernosum
Sign Up to like & getrecommendations! Published in 2019 at "Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy"
DOI: 10.2147/dmso.s205722
Abstract: Objective To investigate the effect of gross saponins of Tribulus terrestris (GSTT) on erectile function in rats resulting from type 2 diabetes mellitus (T2DMED). Methods The T2DMED model was constructed by high-fat and high-sugar feeding… read more here.
Keywords: t2dmed group; cleaved caspase; gstt; tribulus terrestris ... See more keywords
The Mechanism of Bladder Injury in Fetal Rats With Myelomeningocele
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Neurology"
DOI: 10.3389/fneur.2022.861308
Abstract: Background Bladder dysfunction has been implicated as a major cause of progressive renal failure in children with neurogenic bladder. However, its pathogenesis remains unclear. This study aimed to compare the expression of proliferation, apoptosis, and… read more here.
Keywords: bladder; myelomeningocele bladders; fetal rats; expression ... See more keywords
Ultrafine Diesel Exhaust Particles Induce Apoptosis of Oligodendrocytes by Increasing Intracellular Reactive Oxygen Species through NADPH Oxidase Activation
Sign Up to like & getrecommendations! Published in 2022 at "Antioxidants"
DOI: 10.3390/antiox11051031
Abstract: Diesel exhaust particles (DEPs) are a main contributor to air pollution. Ultrafine DEPs can cause neurodegenerative diseases by increasing intracellular reactive oxygen species (ROS). Compared with other cells in the brain, oligodendrocytes responsible for myelination… read more here.
Keywords: diesel exhaust; increasing intracellular; expression; cleaved caspase ... See more keywords
Caspase 3 and Cleaved Caspase 3 Expression in Tumorogenesis and Its Correlations with Prognosis in Head and Neck Cancer: A Systematic Review and Meta-Analysis
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DOI: 10.3390/ijms231911937
Abstract: Head and neck cancer (HNC) is an ascending and agressive disease. The search for new molecular markers is emerging to solve difficulties in diagnosis, risk management, prognosis and effectiveness of treatments. Proteins related to apoptotic… read more here.
Keywords: head neck; review; expression; cleaved caspase ... See more keywords
Protective Effect of Resveratrol on Immortalized Duck Intestinal Epithelial Cells Exposed to H2O2
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27113542
Abstract: Resveratrol is a polyphenolic compound with anti-oxidation effects. The mechanisms underlying the antioxidant effects of resveratrol in duck intestinal epithelial cells remain unclear. The protective effects of resveratrol against oxidative stress induced by H2O2 on… read more here.
Keywords: resveratrol; immortalized duck; duck intestinal; cleaved caspase ... See more keywords