The C-type lectin receptor Clec1A plays an important role in the development of experimental autoimmune encephalomyelitis by enhancing antigen presenting ability of dendritic cells and inducing inflammatory cytokine IL-17.
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DOI: 10.1538/expanim.21-0191
Abstract: Clec1A, a member of C-type lectin receptor family, has a carbohydrate recognition domain in its extracellular region, but no known signaling motif in the cytoplasmic domain. Clec1a is highly expressed in endothelial cells and weakly… read more here.
Keywords: clec1a mice; clec1a; lectin receptor; dendritic cells ... See more keywords