CLEC5A expression can be triggered by spike glycoprotein and may be a potential target for COVID‐19 therapy
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Medical Virology"
DOI: 10.1002/jmv.28427
Abstract: The immune response is crucial for coronavirus disease 19 (COVID‐19) progression, with the participation of proinflammatory cells and cytokines, inducing lung injury and loss of respiratory function. CLEC5A expression on monocytes can be triggered by… read more here.
Keywords: spike glycoprotein; clec5a expression; triggered spike; expression ... See more keywords
CLEC5A Activation in Inflammatory Monocytes: A Mechanism for Enhanced Adaptive Immunity Following COVID-19 mRNA Vaccination in a Preclinical Study
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DOI: 10.3390/v17091233
Abstract: Background: CLEC5A is a C-type lectin expressed by monocytes and neutrophils, playing an important role in innate immunity. Although it has been shown to interact with the spike protein of SARS-CoV-2, its role during vaccination… read more here.
Keywords: clec5a; immunity; clec5a expression; activation ... See more keywords