Nobiletin, sinensetin, and tangeretin are the main perpetrators in clementines provoking food-drug interactions in vitro.
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DOI: 10.1016/j.foodchem.2020.126578
Abstract: For clementine juice, previous data indicate a possible food-drug interaction with substrates of key enzymes responsible for drug metabolism (i.e. cytochrome P450 [CYP] 3A4, CYP1A2). However, which compounds in clementine juice are responsible for these… read more here.
Keywords: juice; food drug; tangeretin; clementine juice ... See more keywords