Sulfonium Triggered Alkyne-Azide Click Cycloaddition.
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DOI: 10.1021/acs.orglett.2c00021
Abstract: Herein, we report the first facile Cu-free click reaction between alkynyl sulfonium and azide at ambient temperatures in aqueous media. DFT computations indicate that the sulfonium group is the key factor to gaining reactivity by… read more here.
Keywords: click cycloaddition; triggered alkyne; sulfonium triggered; sulfonium ... See more keywords
Asymmetric rhodium-catalyzed click cycloaddition to access C–N axially chiral N-triazolyl indoles
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DOI: 10.1039/d3sc00610g
Abstract: The copper-catalyzed azide–alkyne cycloaddition (CuAAC) reaction is regarded as a prime example of “click chemistry”, but the asymmetric click cycloaddition of internal alkynes still remains challenging. A new asymmetric Rh-catalyzed click cycloaddition of N-alkynylindoles with… read more here.
Keywords: catalyzed click; click cycloaddition; axially chiral; chiral triazolyl ... See more keywords
Visible light promoted click [3+2] cycloaddition of aziridine with alkyne: An efficient synthesis of dihydropyrrolidine
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DOI: 10.1055/a-2099-6309
Abstract: A photocatalytic [3+2] cycloaddition of aziridines with activated alkynes is reported under visible light irradiation in the presence of ruthenium catalyst. This chemical transformation provides polysubstituted pyrrolidines in good yields based on the click chemistry… read more here.
Keywords: click cycloaddition; cycloaddition aziridine; light promoted; promoted click ... See more keywords
Intramolecular Click Cycloaddition Reactions: Synthesis of 1,2,3-Triazoles.
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DOI: 10.2174/1570179420666230407103320
Abstract: Click Chemistry, as a powerful tool, has been used for the synthesis of a variety of 1,2,3-triazoles. Among click cycloaddition reactions, intramolecular click reactions carried out in azido-alkyne precursors has not been thoroughly reviewed. Hence,… read more here.
Keywords: click cycloaddition; intramolecular click; cycloaddition reactions; reactions synthesis ... See more keywords