Genome-wide mapping and quantification of DNA damage induced by catechol estrogens using Click-Probe-Seq and LC-MS2
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DOI: 10.1038/s42003-025-07657-0
Abstract: Genotoxic estrogen metabolites generate various DNA lesions; however, their target genes and carcinogenic mechanisms remain unexplored. Here, genome-wide sequencing using click probe enrichment coupled with liquid chromatography-tandem mass spectrometry (Click-Probe-Seq/LC-MS2) is developed to identify damaged… read more here.
Keywords: click probe; using click; damage; probe seq ... See more keywords