Rapid and Modular Assembly of Click Substrates To Assay Enzyme Activity in the Newborn Screening of Lysosomal Storage Disorders
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DOI: 10.1021/acscentsci.8b00668
Abstract: Synthetic substrates play a pivotal role in the development of enzyme assays for medical diagnostics. However, the preparation of these chemical tools often requires multistep synthetic procedures complicating structural optimization and limiting versatility. In particular,… read more here.
Keywords: lysosomal storage; modular assembly; rapid modular; click substrates ... See more keywords