Comprehensive characterization of the Hsp70 interactome reveals novel client proteins and interactions mediated by posttranslational modifications
Sign Up to like & getrecommendations! Published in 2022 at "PLOS Biology"
DOI: 10.1371/journal.pbio.3001839
Abstract: Hsp70 interactions are critical for cellular viability and the response to stress. Previous attempts to characterize Hsp70 interactions have been limited by their transient nature and the inability of current technologies to distinguish direct versus… read more here.
Keywords: characterization hsp70; function; client; client proteins ... See more keywords
In vivo client proteins of the chaperonin GroEL-GroES provide insight into the role of chaperones in protein evolution
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2023.1091677
Abstract: Protein folding is often hampered by intermolecular protein aggregation, which can be prevented by a variety of chaperones in the cell. Bacterial chaperonin GroEL is a ring-shaped chaperone that forms complexes with its cochaperonin GroES,… read more here.
Keywords: client proteins; chaperonin groel; protein evolution; groel groes ... See more keywords