CLImAT-HET: detecting subclonal copy number alterations and loss of heterozygosity in heterogeneous tumor samples from whole-genome sequencing data
Sign Up to like & getrecommendations! Published in 2017 at "BMC Medical Genomics"
DOI: 10.1186/s12920-017-0255-4
Abstract: BackgroundCopy number alterations (CNA) and loss of heterozygosity (LOH) represent a large proportion of genetic structural variations of cancer genomes. These aberrations are continuously accumulated during the procedure of clonal evolution and patterned by phylogenetic… read more here.
Keywords: climat het; cna loh; number alterations; tumor ... See more keywords