Clindamycin use in head and neck surgery elevates the rate of infections in tracheostomies
Sign Up to like & getrecommendations! Published in 2022 at "European Archives of Oto-Rhino-Laryngology"
DOI: 10.1007/s00405-022-07349-z
Abstract: Surgical site infection (SSI) in open surgical tracheostomy (ST) occurs in up to 33% of the cases. SSI can be reduced by a postoperative antibiotic prophylaxis (POAP). The effect of Clindamycin on SSIs in head… read more here.
Keywords: neck surgery; head neck; clindamycin;
Peri-operative, intravenous clindamycin may improve the resolution rate of hypertension after Roux-en-Y gastric bypass in morbidly obese patients
Sign Up to like & getrecommendations! Published in 2019 at "Surgical Endoscopy"
DOI: 10.1007/s00464-019-06687-0
Abstract: BackgroundRecent studies have suggested that potential aberrant alterations in the gastrointestinal microbiome contribute to the development of cardiovascular disease, specifically hypertension. Bariatric surgery produces significant sustained weight loss and hypertension resolution likely through multiple mechanisms… read more here.
Keywords: peri operative; resolution; clindamycin; hypertension ... See more keywords
Enforced lysosomal biogenesis rescues erythromycin- and clindamycin-induced mitochondria-mediated cell death in human cells
Sign Up to like & getrecommendations! Published in 2019 at "Molecular and Cellular Biochemistry"
DOI: 10.1007/s11010-019-03585-w
Abstract: Antibiotics are the front-line treatment against many bacterial infectious diseases in human. The excessive and long-term use of antibiotics in human cause several side effects. It is important to understand the underlying molecular mechanisms of… read more here.
Keywords: death; clindamycin; cell death; cldm ... See more keywords
A human bone infection organ model for biomaterial research.
Sign Up to like & getrecommendations! Published in 2022 at "Acta biomaterialia"
DOI: 10.1016/j.actbio.2022.03.020
Abstract: The aim of this work was to establish an organ model for staphylococcal infection of human bone samples and to investigate the influence and efficacy of a microporous β-tricalcium phosphate ceramic (β-TCP, RMS Foundation) loaded… read more here.
Keywords: bone; human bone; infection; bone infection ... See more keywords
Design and characterization of clindamycin-loaded nanofiber patches composed of polyvinyl alcohol and tamarind seed gum and fabricated by electrohydrodynamic atomization
Sign Up to like & getrecommendations! Published in 2018 at "Asian Journal of Pharmaceutical Sciences"
DOI: 10.1016/j.ajps.2018.01.002
Abstract: In this study, we developed a polymeric nanofiber patch (PNP) for topical disease treatment using electrohydrodynamic atomization (EHDA). The nanofibers were prepared using various concentrations of polyvinyl alcohol (PVA) and tamarind seed gum and loaded… read more here.
Keywords: seed; electrohydrodynamic atomization; clindamycin; gum ... See more keywords
Susceptibility of bacterial vaginosis (BV)-associated bacteria to secnidazole compared to metronidazole, tinidazole and clindamycin.
Sign Up to like & getrecommendations! Published in 2017 at "Anaerobe"
DOI: 10.1016/j.anaerobe.2017.05.005
Abstract: Secnidazole, a 5-nitroimidazole with a longer half-life, is structurally related to metronidazole and tinidazole. For treatment of bacterial vaginosis (BV), secnidazole is a suitable single-dose oral drug having a longer serum half-life than metronidazole. The… read more here.
Keywords: tinidazole; metronidazole tinidazole; clindamycin; bacterial vaginosis ... See more keywords
Intra-peritoneal abscess after an abdominal hysterectomy involving Cutibacterium avidum (former Propionibacterium avidum) highly resistant to clindamycin.
Sign Up to like & getrecommendations! Published in 2019 at "Anaerobe"
DOI: 10.1016/j.anaerobe.2019.06.013
Abstract: Cutibacterium avidum is a gram-positive anaerobic rod belonging to the cutaneous group of human bacteria with preferential colonization of sweat glands in moist areas. The microorganism rarely cause disease, generally delayed prosthetic joint infections (PJIs).… read more here.
Keywords: intra peritoneal; cutibacterium avidum; clindamycin; peritoneal abscess ... See more keywords
Development and validation of a simple chromatographic method for simultaneous determination of clindamycin phosphate and rifampicin in skin permeation studies
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Pharmaceutical and Biomedical Analysis"
DOI: 10.1016/j.jpba.2018.07.007
Abstract: Graphical abstract Figure. No caption available. HighlightsHPLC method for simultaneous determination of clindamycin and rifampicin in skin.Method with an extreme capacity of drugs recovery from skin matrix.The HPLC method complied with all international regulatory requirements.The… read more here.
Keywords: skin; method; clindamycin; cdm ... See more keywords
Visual Recognition and Detection of Clindamycin by Au@Ag Core–Shell Nanoparticles
Sign Up to like & getrecommendations! Published in 2021 at "ACS Omega"
DOI: 10.1021/acsomega.1c01028
Abstract: The work described a new colorimetric sensor for the quantitative detection of clindamycin based on Au@Ag core–shell nanoparticles (Au@Ag NPs). The obtained Au@Ag NPs were characterized by transmission electron microscopy (TEM) and ultraviolet and visible… read more here.
Keywords: detection; core shell; shell nanoparticles; clindamycin ... See more keywords
Co-delivery of isotretinoin and clindamycin by phospholipid-based mixed micellar system confers synergistic effect for treatment of acne vulgaris
Sign Up to like & getrecommendations! Published in 2021 at "Expert Opinion on Drug Delivery"
DOI: 10.1080/17425247.2021.1919618
Abstract: Abstract Background The combination therapy of Isotretinoin (ITR) and antibacterial formulations administered through topical route suffer from several limitations including reduced therapeutic efficacy and low patient-compliance. Experiment The present study aimed to develop biocompatible lipid-based… read more here.
Keywords: based mixed; delivery; efficacy; clindamycin ... See more keywords
A Phase 1 pharmacokinetic study of a single-dose bioadhesive clindamycin 2% gel for bacterial vaginosis
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Antimicrobial Chemotherapy"
DOI: 10.1093/jac/dkac386
Abstract: Abstract Objectives To evaluate pharmacokinetics (PK) of a single dose of an investigational 2% clindamycin phosphate vaginal gel in healthy women by assessment of plasma and vaginal clindamycin concentrations over 7 days, and assess safety. Methods… read more here.
Keywords: clindamycin; single dose; gel; clindamycin phosphate ... See more keywords