Evaluation of Poly(glycidyl methacrylate)-Coated Column for Enantioseparation with Azithromycin Lactobionate and Clindamycin Phosphate as Chiral Selectors in Capillary Electrophoresis
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DOI: 10.1007/s10337-021-04029-8
Abstract: In this study, a poly(glycidyl methacrylate) nanoparticle (PGMA NP)-coated column system with two antibiotics as selector was constructed for enantioseparation. The PGMA NP coating inside the capillary columns could be easily introduced by a simple… read more here.
Keywords: poly glycidyl; coated column; clindamycin phosphate; azithromycin lactobionate ... See more keywords
Harnessing nanotechnology for enhanced topical delivery of clindamycin phosphate
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DOI: 10.1016/j.jddst.2019.101253
Abstract: Abstract The treatment of acne warrants development of formulation aiming to enhance topical delivery with minimum systemic absorption. The aim of present study was to develop, optimize and characterize clindamycin phosphate-loaded nanostructured lipid carriers (CP-NLC)… read more here.
Keywords: enhanced topical; delivery; clindamycin phosphate; nanotechnology ... See more keywords
A Phase 1 pharmacokinetic study of a single-dose bioadhesive clindamycin 2% gel for bacterial vaginosis
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DOI: 10.1093/jac/dkac386
Abstract: Abstract Objectives To evaluate pharmacokinetics (PK) of a single dose of an investigational 2% clindamycin phosphate vaginal gel in healthy women by assessment of plasma and vaginal clindamycin concentrations over 7 days, and assess safety. Methods… read more here.
Keywords: clindamycin; single dose; gel; clindamycin phosphate ... See more keywords
Triple‐combination clindamycin phosphate 1.2%/benzoyl peroxide 3.1%/adapalene 0.15% gel for moderate‐to‐severe acne in children and adolescents: Randomized phase 2 study
Sign Up to like & getrecommendations! Published in 2023 at "Pediatric Dermatology"
DOI: 10.1111/pde.15283
Abstract: Topical clindamycin phosphate 1.2%/benzoyl peroxide 3.1%/adapalene 0.15% gel (IDP‐126) is the first fixed‐dose triple‐combination formulation in development for acne. This post hoc analysis investigated efficacy and safety of IDP‐126 in children and adolescents with moderate‐to‐severe… read more here.
Keywords: peroxide adapalene; triple combination; phosphate benzoyl; clindamycin phosphate ... See more keywords