Clinical adverse effects of natalizumab
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DOI: 10.1097/md.0000000000011507
Abstract: Background: Natalizumab (NAT), a humanized monoclonal antibody, which binds in both &agr;4&bgr;1 integrins and &agr;4&bgr;7 integrins, is approved for the treatment of multiple sclerosis (MS) and Crohn's disease (CD). An uncommon but serious adverse event… read more here.
Keywords: aes; medicine; effects natalizumab; clinical adverse ... See more keywords
Weight cycling and risk of clinical adverse events in patients with heart failure with preserved ejection fraction: a post-hoc analysis of TOPCAT
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DOI: 10.3389/fendo.2023.1159826
Abstract: Background Previous studies hardly evaluated the association of variability of body mass index (BMI) or waist circumference with clinical adverse events and investigated whether weight cycling had an effect on the prognosis of patients with… read more here.
Keywords: heart failure; clinical adverse; analysis; heart ... See more keywords
Dose-Dependent Biphasic Action of Quetiapine on AMPK Signalling via 5-HT7 Receptor: Exploring Pathophysiology of Clinical and Adverse Effects of Quetiapine
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DOI: 10.3390/ijms23169103
Abstract: Recent pharmacological studies indicated that the modulation of tripartite-synaptic transmission plays important roles in the pathophysiology of schizophrenia, mood disorders and adverse reactions. Therefore, to explore the mechanisms underlying the clinical and adverse reactions to… read more here.
Keywords: ht7 receptor; ampk signalling; dose dependent; clinical adverse ... See more keywords