Implantable Therapeutic Reservoir Systems for Diverse Clinical Applications in Large Animal Models.
Sign Up to like & getrecommendations! Published in 2020 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202000305
Abstract: Regenerative medicine approaches, specifically stem cell technologies, have demonstrated significant potential to treat a diverse array of pathologies. However, such approaches have resulted in a modest clinical benefit, which may be attributed to poor cell… read more here.
Keywords: reservoir; large animal; delivery; target ... See more keywords
Therapeutic DNAzymes: From Structure Design to Clinical Applications.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced materials"
DOI: 10.1002/adma.202300374
Abstract: Therapeutic DNAzymes have unceasingly intrigued the scientific community owing to their prosperous gene regulation capability. The efficacy of DNAzymes against many types of diseases has been extensively studied for over two decades. However, the high… read more here.
Keywords: clinical applications; design; design clinical; therapeutic dnazymes ... See more keywords
Future Prospects for Clinical Applications of Nanocarbons Focusing on Carbon Nanotubes
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DOI: 10.1002/advs.202201214
Abstract: Over the past 15 years, numerous studies have been conducted on the use of nanocarbons as biomaterials towards such applications as drug delivery systems, cancer therapy, and regenerative medicine. However, the clinical use of nanocarbons… read more here.
Keywords: carbon; clinical applications; carbon nanotubes; applications nanocarbons ... See more keywords
A field guide for cancer diagnostics using cell‐free DNA: From principles to practice and clinical applications
Sign Up to like & getrecommendations! Published in 2018 at "Genes"
DOI: 10.1002/gcc.22517
Abstract: Recently, many genome‐wide profiling studies provided insights into the molecular make‐up of major cancer types. The deeper understanding of these genetic alterations and their functional consequences led to the discovery of novel therapeutic opportunities improving… read more here.
Keywords: dna; free dna; cell free; clinical applications ... See more keywords
Breast PET/MRI Hybrid Imaging and Targeted Tracers
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Magnetic Resonance Imaging"
DOI: 10.1002/jmri.28431
Abstract: The recent introduction of hybrid positron emission tomography/magnetic resonance imaging (PET/MRI) as a promising imaging modality for breast cancer assessment has prompted fervent research activity on its clinical applications. The current knowledge regarding the possible… read more here.
Keywords: pet mri; magnetic resonance; clinical applications; breast pet ... See more keywords
Potential clinical applications of phytopharmaceuticals for the in‐patient management of coagulopathies in COVID‐19
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DOI: 10.1002/ptr.7408
Abstract: Thrombotic complications occur in many cardiovascular pathologies and have been demonstrated in COVID‐19. The currently used antithrombotic drugs are not free of adverse reactions, and COVID‐19 patients in particular, when treated with a therapeutic dose… read more here.
Keywords: phytopharmaceuticals patient; clinical applications; potential clinical; applications phytopharmaceuticals ... See more keywords
Direct Thermal Growth of Gold Nanopearls on 3D Interweaved Hydrophobic Fibers as Ultrasensitive Portable SERS Substrates for Clinical Applications.
Sign Up to like & getrecommendations! Published in 2023 at "Small"
DOI: 10.1002/smll.202207404
Abstract: Surface-enhanced Raman spectroscopy (SERS)-based biosensors have attracted much attention for their label-free detection, ultrahigh sensitivity, and unique molecular fingerprinting. In this study, a wafer-scale, ultrasensitive, highly uniform, paper-based, portable SERS detection platform featuring abundant and… read more here.
Keywords: direct thermal; clinical applications; portable sers; gold nanopearls ... See more keywords
Biological functions and clinical applications of exosomal non-coding RNAs in hepatocellular carcinoma
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DOI: 10.1007/s00018-019-03215-0
Abstract: Hepatocellular carcinoma (HCC) is one of the most common malignancies worldwide, with a high mortality rate. Its dismal prognosis is attributed to late diagnosis, high risk of recurrence and drug resistance. To improve the survival… read more here.
Keywords: hepatocellular carcinoma; coding rnas; non coding; clinical applications ... See more keywords
The biological functions and clinical applications of exosomes in lung cancer
Sign Up to like & getrecommendations! Published in 2019 at "Cellular and Molecular Life Sciences"
DOI: 10.1007/s00018-019-03233-y
Abstract: Lung cancer remains the leading cause of cancer-related death worldwide, and the high incidence rates are worrisome. Exosomes are a class of extracellular vesicles secreted by most cells, including RNAs, proteins and lipids. Exosomes can… read more here.
Keywords: biological functions; exosomes lung; clinical applications; lung cancer ... See more keywords
Principles of three-dimensional printing and clinical applications within the abdomen and pelvis
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DOI: 10.1007/s00261-018-1554-8
Abstract: Improvements in technology and reduction in costs have led to widespread interest in three-dimensional (3D) printing. 3D-printed anatomical models contribute to personalized medicine, surgical planning, and education across medical specialties, and these models are rapidly… read more here.
Keywords: three dimensional; within abdomen; principles three; abdomen pelvis ... See more keywords
SciKit-Surgery: compact libraries for surgical navigation
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DOI: 10.1007/s11548-020-02180-5
Abstract: Purpose This paper introduces the SciKit-Surgery libraries, designed to enable rapid development of clinical applications for image-guided interventions. SciKit-Surgery implements a family of compact, orthogonal, libraries accompanied by robust testing, documentation, and quality control. SciKit-Surgery… read more here.
Keywords: scikit surgery; surgery; surgery libraries; clinical applications ... See more keywords