Optimized Infliximab Induction Predicts Better Long-Term Clinical and Biomarker Outcomes Compared to Standard Induction Dosing
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Pediatric Gastroenterology and Nutrition"
DOI: 10.1097/mpg.0000000000003587
Abstract: Objectives: To evaluate the efficacy of standard and optimized infliximab induction dosing in attaining corticosteroid (CS) free clinical remission at week 52 and the effect that post-induction trough levels have on long-term outcome. Methods: Inflammatory… read more here.
Keywords: clinical biomarker; long term; infliximab induction; induction ... See more keywords
Sclerostin: From Molecule to Clinical Biomarker
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DOI: 10.3390/ijms23094751
Abstract: Sclerostin, a glycoprotein encoded by the SOST gene, is mainly produced by mature osteocytes and is a critical regulator of bone formation through its inhibitory effect on Wnt signaling. Osteocytes are differentiated osteoblasts that form… read more here.
Keywords: clinical biomarker; sost gene; sclerostin; sclerostin molecule ... See more keywords