Clinical breakpoint meropenem concentration modulate outer membrane vesicle production in enterotoxigenic Bacteroides fragilis
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DOI: 10.1007/s00203-025-04549-z
Abstract: Antibiotic concentrations at clinical breakpoint levels can influence bacterial physiology and virulence responses, yet their effects on outer membrane vesicle (OMV) production in anaerobic pathogens remain understudied. This study examined how breakpoint meropenem concentrations affect… read more here.
Keywords: breakpoint meropenem; breakpoint; vesicle; clinical breakpoint ... See more keywords
Optimal Regimens and Clinical Breakpoint of Avilamycin Against Clostridium perfringens in Swine Based on PK-PD Study
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DOI: 10.3389/fphar.2022.769539
Abstract: Clostridium perfringens causes significant morbidity and mortality in swine worldwide. Avilamycin showed no cross resistance and good activity for treatment of C. perfringens. The aim of this study was to formulate optimal regimens of avilamycin… read more here.
Keywords: optimal regimens; clinical breakpoint; clostridium perfringens; study ... See more keywords
Clinical Breakpoint of Apramycin to Swine Salmonella and Its Effect on Ileum Flora
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DOI: 10.3390/ijms23031424
Abstract: The purpose of this study was to establish the clinical breakpoint (CBP) of apramycin (APR) against Salmonella in swine and evaluate its effect on intestinal microbiota. The CBP was established based on three cutoff values… read more here.
Keywords: ileum; ileum flora; clinical breakpoint; effect ... See more keywords