Exploring clinical chemistry markers in amyotrophic lateral sclerosis: insights into survival and disease trajectories
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Neurology"
DOI: 10.1007/s00415-024-12774-7
Abstract: Commonly measured clinical chemistry markers might be indicative of survival and disease progression in amyotrophic lateral sclerosis (ALS). In a cohort study of 270 ALS patients diagnosed from April 2014 to May 2021 in Stockholm,… read more here.
Keywords: chemistry; survival disease; clinical chemistry; amyotrophic lateral ... See more keywords
Challenges amid COVID-19 times - Review of the changing practices in a clinical chemistry laboratory from a developing country
Sign Up to like & getrecommendations! Published in 2020 at "Annals of Medicine and Surgery"
DOI: 10.1016/j.amsu.2020.06.004
Abstract: Corona Virus Disease 2019 (COVID-19) pandemic is the defining global health crisis of our time. Compared with its neighbors China and Iran, which were rated as epi-centers of the outbreak, Pakistan has lower standards of… read more here.
Keywords: chemistry; chemistry laboratory; clinical chemistry; challenges amid ... See more keywords
First two-reagent vitamin D assay for general clinical chemistry.
Sign Up to like & getrecommendations! Published in 2018 at "Clinical biochemistry"
DOI: 10.1016/j.clinbiochem.2018.03.017
Abstract: BACKGROUND Vitamin D is a lipid-soluble molecule that plays key physiological roles in the metabolism of calcium, phosphate and magnesium. Recent studies show that deficiency in vitamin D is linked to cardiovascular diseases, autoimmune diseases… read more here.
Keywords: chemistry; general clinical; clinical chemistry; vitamin assay ... See more keywords
Performance specifications and six sigma theory: Clinical chemistry and industry compared.
Sign Up to like & getrecommendations! Published in 2018 at "Clinical biochemistry"
DOI: 10.1016/j.clinbiochem.2018.04.002
Abstract: Analytical performance specifications are crucial in test development and quality control. Although consensus has been reached on the use of biological variation to derive these specifications, no consensus has been reached which model should be… read more here.
Keywords: performance specifications; six sigma; industry; chemistry ... See more keywords
Analytical validation of 39 clinical chemistry tests and 17 immunoassays on the Alinity analytical system
Sign Up to like & getrecommendations! Published in 2022 at "Scandinavian Journal of Clinical and Laboratory Investigation"
DOI: 10.1080/00365513.2022.2056856
Abstract: Abstract The aim of this study was to perform the analytical validation of Alinity c and i analyzers (Abbott Laboratories, Chicago, IL, USA) for 39 clinical chemistry tests and 17 immunoassays. Precision was evaluated at… read more here.
Keywords: chemistry; alinity; clinical chemistry; analytical validation ... See more keywords
Assessment of large language models in medical quizzes for clinical chemistry and laboratory management: implications and applications for healthcare artificial intelligence
Sign Up to like & getrecommendations! Published in 2025 at "Scandinavian Journal of Clinical and Laboratory Investigation"
DOI: 10.1080/00365513.2025.2466054
Abstract: Abstract Large language models (LLMs) have demonstrated high performance across various fields due to their ability to understand, generate, and manipulate human language. However, their potential in specialized medical domains, such as clinical chemistry and… read more here.
Keywords: chemistry; language; laboratory management; clinical chemistry ... See more keywords
Effects of Freezing and Thawing Procedures on Selected Clinical Chemistry Parameters in Plasma.
Sign Up to like & getrecommendations! Published in 2020 at "Biopreservation and biobanking"
DOI: 10.1089/bio.2020.0005
Abstract: Introduction: Measurements from frozen sample collections are important key indicators in clinical studies. It is a prime concern of biobanks and laboratories to minimize preanalytical bias and variance through standardization. In this study, we aimed… read more here.
Keywords: effects freezing; chemistry; clinical chemistry; baseline ... See more keywords
B-039 Evaluating Inter-Analytic Module Immunoassay Carryover
Sign Up to like & getrecommendations! Published in 2024 at "Clinical Chemistry"
DOI: 10.1093/clinchem/hvae106.403
Abstract: Integrated analytical systems contain both clinical chemistry analyzers and immunoassay analyzers. Immunoassays can be assigned high priority based on potential sample carryover from sample probes used in clinical chemistry analyzers. The priority designation, assigned by… read more here.
Keywords: chemistry; clinical chemistry; roche diagnostics; carryover ... See more keywords
Merging clinical chemistry biomarker data with a COPD database - building a clinical infrastructure for proteomic studies
Sign Up to like & getrecommendations! Published in 2017 at "Proteome Science"
DOI: 10.1186/s12953-017-0116-2
Abstract: BackgroundData from biological samples and medical evaluations plays an essential part in clinical decision making. This data is equally important in clinical studies and it is critical to have an infrastructure that ensures that its… read more here.
Keywords: biomarker data; chemistry; infrastructure; copd ... See more keywords
Routine clinical chemistry and haematological test reference intervals for healthy adults in the Bhutanese population
Sign Up to like & getrecommendations! Published in 2022 at "PLoS ONE"
DOI: 10.1371/journal.pone.0273778
Abstract: Laboratory medicine plays a critical role in the modern healthcare system, and it is reported to influence 60–70% of clinical decision makings. The quantitative laboratory test results are interpreted by comparing to the Reference Intervals… read more here.
Keywords: bhutanese population; chemistry haematological; chemistry; clinical chemistry ... See more keywords
Reference intervals for common clinical chemistry parameters in healthy adults of Northeast Ethiopia
Sign Up to like & getrecommendations! Published in 2022 at "PLOS ONE"
DOI: 10.1371/journal.pone.0276825
Abstract: Background Clinical chemistry reference intervals are important tools for health evaluation, diagnosis, prognosis and monitoring adverse events. Currently used reference intervals in most African countries including Ethiopia are mainly derived from Western populations, despite studies… read more here.
Keywords: reference; chemistry parameters; chemistry; clinical chemistry ... See more keywords