Leishmania amazonensis from distinct clinical forms/hosts has polymorphisms in Lipophosphoglycans, displays variations in immunomodulatory properties and, susceptibility to antileishmanial drugs
Sign Up to like & getrecommendations! Published in 2022 at "Cell Biology International"
DOI: 10.1002/cbin.11880
Abstract: Lipophosphoglycan (LPG), the major Leishmania glycoconjugate, induces pro‐inflammatory/immunosuppressive innate immune responses. Here, we evaluated functional/biochemical LPG properties from six Leishmania amazonensis strains from different hosts/clinical forms. LPGs from three strains (GV02, BA276, and LV79) had… read more here.
Keywords: susceptibility antileishmanial; clinical forms; amazonensis; side chains ... See more keywords
Simultaneous analysis of multiple T helper subsets in leprosy reveals distinct patterns of Th1, Th2, Th17 and Tregs markers expression in clinical forms and reactional events
Sign Up to like & getrecommendations! Published in 2017 at "Medical Microbiology and Immunology"
DOI: 10.1007/s00430-017-0519-9
Abstract: Leprosy is a chronic infectious disease caused by Mycobacterium leprae. Previous studies have demonstrated that the difference among clinical forms of leprosy can be associated with the immune response of patients, mainly by T helper… read more here.
Keywords: clinical forms; reactional events; th17 tregs; th2 th17 ... See more keywords
Distribution of microRNA profiles in pre-clinical and clinical forms of murine and human prion disease
Sign Up to like & getrecommendations! Published in 2021 at "Communications Biology"
DOI: 10.1038/s42003-021-01868-x
Abstract: Prion diseases are distinguished by long pre-clinical incubation periods during which prions actively propagate in the brain and cause neurodegeneration. In the pre-clinical stage, we hypothesize that upon prion infection, transcriptional changes occur that can… read more here.
Keywords: clinical forms; prion; forms murine; disease ... See more keywords
Human papilloma virus-16-specific CD8+ T-cell expansions characterize different clinical forms of lichen planus and not lichen sclerosus et atrophicus.
Sign Up to like & getrecommendations! Published in 2023 at "Experimental dermatology"
DOI: 10.1111/exd.14788
Abstract: Lichen planus (LP) is a cutaneomucosal chronic inflammatory disease characterized by a CD8+ cytotoxic T‐lymphocytes (CTL) infiltrate. In erosive oral LP, we found HPV16‐specific activated CTL in lesions, supporting a pathogenic contribution of HPV16. Here,… read more here.
Keywords: clinical forms; sclerosus atrophicus; forms lichen; specific cd8 ... See more keywords
Efficacy and Safety of Ibrutinib in Combination with Rituximab As Frontline Treatment for Indolent Clinical Forms of Mantle Cell Lymphoma (MCL): Preliminary Results of Geltamo IMCL-2015 Phase II Trial
Sign Up to like & getrecommendations! Published in 2019 at "Blood"
DOI: 10.1182/blood-2019-122191
Abstract: Background: MCL is a heterogeneous disease and the existence of indolent clinical forms is increasingly recognized although their biological ground is not fully elucidated. The aim of this study was to propose a frontline tailored… read more here.
Keywords: clinical forms; treatment; consultancy; research funding ... See more keywords
Two different clinical forms of squamous cell carcinoma (SCC) in the perineum and vulva of two mares
Sign Up to like & getrecommendations! Published in 2020 at "BMC Veterinary Research"
DOI: 10.1186/s12917-020-02678-9
Abstract: Background Genital malignant neoplasms in mares are relatively rare. The treatment involve surgical removal of the tumour masses, chemotherapy or both. Case presentation Two elderly warmblood mares, aged 16 and 20 were presented in University… read more here.
Keywords: clinical forms; forms squamous; squamous cell; different clinical ... See more keywords
Ibrutinib in Combination With Rituximab for Indolent Clinical Forms of Mantle Cell Lymphoma (IMCL-2015): A Multicenter, Open-Label, Single-Arm, Phase II Trial
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.21.02321
Abstract: PURPOSE The need for an individualized management of indolent clinical forms in mantle cell lymphoma (MCL) is increasingly recognized. We hypothesized that a tailored treatment with ibrutinib in combination with rituximab (IR) could obtain significant… read more here.
Keywords: clinical forms; indolent clinical; mantle cell; cell lymphoma ... See more keywords
Analysis of clinical data and T helper 1/T helper 2 responses in patients with different clinical forms of leprosy.
Sign Up to like & getrecommendations! Published in 2017 at "Revista da Sociedade Brasileira de Medicina Tropical"
DOI: 10.1590/0037-8682-0426-2016
Abstract: INTRODUCTION: Currently, there are no laboratory tests or sensitive and specific molecular markers for the early diagnosis of leprosy. The aim of this study was to analyze the clinical characteristics of patients with leprosy and… read more here.
Keywords: clinical forms; lepromatous leprosy; helper; different clinical ... See more keywords
Biotechnological and Immunological Platforms Based on PGL-I Carbohydrate-Like Peptide of Mycobacterium leprae for Antibodies Detection Among Leprosy Clinical Forms
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2020.00429
Abstract: Phenolic glycolipid I (PGL-I) is an abundant antigen on the Mycobacterium leprae cell wall, commonly used for operational classification of leprosy patients. Our aim was to develop PGL-I mimotopes with similar characteristics and functions of… read more here.
Keywords: leprosy clinical; clinical forms; mycobacterium leprae; pgl ... See more keywords
Effect of Photobiomodulation on Atrophic–Erosive Clinical Forms of Oral Lichen Planus: A Systematic Review
Sign Up to like & getrecommendations! Published in 2022 at "Dentistry Journal"
DOI: 10.3390/dj10120221
Abstract: Introduction. Oral lichen planus is a chronic autoimmune inflammatory disease of unknown origin, characterized by various clinical forms of which the atrophic–erosive causes patients the greatest symptomatology. For this reason, there are different treatments that… read more here.
Keywords: clinical forms; oral lichen; photobiomodulation; lichen planus ... See more keywords
Perceived Stress in Relation to Demographics and Clinical Forms among Patients with Infective Endocarditis: A Cross-Sectional Study
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Environmental Research and Public Health"
DOI: 10.3390/ijerph192114073
Abstract: (1) Background: Infective endocarditis (IE) is a disease of the endocardial surface of the heart, caused by infection of the native or prosthetic valve or an indwelling cardiac device. Apart from IE predisposing risk factors… read more here.
Keywords: infective endocarditis; clinical forms; cross sectional; forms among ... See more keywords