Right Ventricular Sarcomere Contractile Depression and the Role of Thick Filament Activation in Human Heart Failure With Pulmonary Hypertension.
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DOI: 10.1161/circulationaha.123.064717
Abstract: BACKGROUND Right ventricular (RV) contractile dysfunction commonly occurs and worsens outcomes in patients with heart failure with reduced ejection fraction and pulmonary hypertension (HFrEF-PH). However, such dysfunction often goes undetected by standard clinical RV indices,… read more here.
Keywords: clinical function; heart failure; drx; thick filament ... See more keywords
MR biomarkers predict clinical function in Duchenne muscular dystrophy
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DOI: 10.1212/wnl.0000000000009012
Abstract: Objective To investigate the potential of lower extremity magnetic resonance (MR) biomarkers to serve as endpoints in clinical trials of therapeutics for Duchenne muscular dystrophy (DMD) by characterizing the longitudinal progression of MR biomarkers over… read more here.
Keywords: duchenne muscular; mri; muscular dystrophy; clinical function ... See more keywords