Automatic auditory processing features in distinct subtypes of patients at clinical high risk for psychosis: Forecasting remission with mismatch negativity
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DOI: 10.1002/hbm.26021
Abstract: Individuals at clinical high risk (CHR) for psychosis exhibit a compromised mismatch negativity (MMN) response, which indicates dysfunction of pre‐attentive deviance processing. Event‐related potential and time‐frequency (TF) information, in combination with clinical and cognitive profiles,… read more here.
Keywords: processing; frequency; high risk; remission ... See more keywords
Peer delivered services in mental health care in 2018: infancy or adolescence?
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DOI: 10.1002/wps.20530
Abstract: ing effect on reward processing. Studies examining the neural response to rewarding stimuli in schizophrenia suggest that second generation antipsychotics are associated with intact response to reward outcomes in the ventral striatum. Since individuals with… read more here.
Keywords: schizophrenia; high risk; individuals schizotypy; anhedonia ... See more keywords
Bullying in clinical high risk for psychosis participants from the NAPLS-3 cohort
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DOI: 10.1007/s00127-022-02239-5
Abstract: Bullying is associated with a heightened risk for poor outcomes, including psychosis. This study aimed to replicate previous findings on bullying prevalence in clinical high-risk (CHR) individuals, to assess the longitudinal course of clinical and… read more here.
Keywords: risk; clinical high; high risk; chr individuals ... See more keywords
Postural sway and neurocognition in individuals meeting criteria for a clinical high-risk syndrome
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DOI: 10.1007/s00406-021-01234-2
Abstract: Neurocognitive deficits are implicated in individuals that meet criteria for a clinical high-risk (CHR) syndrome. Evidence in patients with schizophrenia suggests that cerebellar dysfunction may underlie neurocognitive deficits. However, little research has examined if similar… read more here.
Keywords: risk; postural sway; criteria clinical; high risk ... See more keywords
Hippocampal Pathology in Clinical High-Risk Patients and the Onset of Schizophrenia
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DOI: 10.1016/j.biopsych.2019.09.022
Abstract: BACKGROUND We examined neuroimaging-derived hippocampal biomarkers in subjects at clinical high risk (CHR) for psychosis to further characterize the pathophysiology of early psychosis. We hypothesized that glutamate hyperactivity, reflected by increased metabolic activity derived from… read more here.
Keywords: high risk; magnetic resonance; pathology; clinical high ... See more keywords
Checking the predictive accuracy of basic symptoms against ultra high-risk criteria and testing of a multivariable prediction model: Evidence from a prospective three-year observational study of persons at clinical high-risk for psychosis
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DOI: 10.1016/j.eurpsy.2017.05.026
Abstract: Abstract Background: The aim of this study was to critically examine the prognostic validity of various clinical high-risk (CHR) criteria alone and in combination with additional clinical characteristics. Methods: A total of 188 CHR positive… read more here.
Keywords: risk; high risk; clinical high; predictive accuracy ... See more keywords
Neurocognitive dysfunction in subjects at clinical high risk for psychosis: A meta-analysis.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of psychiatric research"
DOI: 10.1016/j.jpsychires.2018.05.001
Abstract: Findings of neurocognitive dysfunction in subjects at Clinical High Risk for Psychosis (CHR-P) have been controversial. This meta-analysis systematically examined studies of neurocognitive functions using the MATRICS Consensus Cognitive Battery (MCCB) in CHR-P. An independent… read more here.
Keywords: dysfunction subjects; neurocognitive dysfunction; meta; smd ... See more keywords
Acute effects of smoked marijuana in marijuana smokers at clinical high-risk for psychosis: A preliminary study
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DOI: 10.1016/j.psychres.2017.07.070
Abstract: Marijuana use is associated with psychosis, but its effects are understudied in individuals with preexisting risk for psychotic disorders. This preliminary study examined the acute psychological and physiological effects of smoked marijuana (0.0% or 5.5%… read more here.
Keywords: marijuana; risk; preliminary study; effects smoked ... See more keywords
Family history of psychosis in youth at clinical high risk: A replication study
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DOI: 10.1016/j.psychres.2022.114480
Abstract: Having a first-degree relative with a psychotic disorder increases an individual's risk for developing psychosis to 10% compared to 1% in the general population. The impact of being at family high-risk for psychosis (FHR) has… read more here.
Keywords: risk; clinical high; youth clinical; high risk ... See more keywords
Brain network characteristics separating individuals at clinical high risk for psychosis into normality or psychosis
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DOI: 10.1016/j.schres.2017.03.028
Abstract: We aimed to separate individuals at clinical high risk for psychosis (CHR) state into subgroups according to neurobiological characteristics using structural and functional network constructs and examine their clinical characteristics. Structural diffusion tensor imaging and… read more here.
Keywords: individuals clinical; network; high risk; clinical high ... See more keywords
Impact of lifetime traumatic experiences on suicidality and likelihood of conversion in a cohort of individuals at clinical high-risk for psychosis
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DOI: 10.1016/j.schres.2017.09.006
Abstract: Recent research suggests that trauma history (TH) is a strong socio-environmental risk factor for the development of psychosis. While reported rates of childhood trauma are higher among individuals at clinical high-risk (CHR) for psychosis than… read more here.
Keywords: risk; individuals clinical; high risk; conversion ... See more keywords