Clinical impact of the VOLO optimizer on treatment plan quality and clinical treatment efficiency for CyberKnife
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Applied Clinical Medical Physics"
DOI: 10.1002/acm2.12851
Abstract: Abstract With the recent CyberKnife treatment planning system (TPS) upgrade from Precision 1.0 to Precision 2.0, the new VOLO optimizer was released for plan optimization. The VOLO optimizer sought to overcome some of the limitations… read more here.
Keywords: plan quality; clinical impact; treatment; volo optimizer ... See more keywords
Evaluation of the clinical impact of the differences between planned and delivered dose in prostate cancer radiotherapy based on CT‐on‐rails IGRT and patient‐reported outcome scores
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Applied Clinical Medical Physics"
DOI: 10.1002/acm2.13780
Abstract: Abstract Purpose To estimate the clinical impact of differences between delivered and planned dose using dose metrics and normal tissue complication probability (NTCP) modeling. Methods Forty‐six consecutive patients with prostate adenocarcinoma between 2010 and 2015… read more here.
Keywords: planned delivered; delivered doses; patient; clinical impact ... See more keywords
Clinical impact of sedentary behaviors in adult survivors of acute lymphoblastic leukemia: A report from the St. Jude Lifetime Cohort study
Sign Up to like & getrecommendations! Published in 2018 at "Cancer"
DOI: 10.1002/cncr.31162
Abstract: Sedentary behaviors are associated with poor health outcomes in the general population, but their clinical impact on adult survivors of childhood acute lymphoblastic leukemia (ALL) has not been characterized to date. In the current study,… read more here.
Keywords: sedentary behaviors; adult survivors; lymphoblastic leukemia; clinical impact ... See more keywords
Landscape and clinical impact of NOTCH mutations in newly diagnosed acute myeloid leukemia
Sign Up to like & getrecommendations! Published in 2022 at "Cancer"
DOI: 10.1002/cncr.34534
Abstract: NOTCH mutations (NOTCHmut) are recognized as major oncogenic drivers associated with controversial clinical impact on T‐cell acute lymphoblastic leukemia (T‐ALL), whereas their clinical value on acute myeloid leukemia (AML) is poorly defined. read more here.
Keywords: myeloid leukemia; notch mutations; leukemia; acute myeloid ... See more keywords
Clinical impact of minimal residual disease and genetic subtypes on the prognosis of childhood acute lymphoblastic leukemia
Sign Up to like & getrecommendations! Published in 2022 at "Cancer"
DOI: 10.1002/cncr.34606
Abstract: This study analyzed data from two consecutive protocols for children newly diagnosed with acute lymphoblastic leukemia (ALL) to determine the clinical impact of minimal/measurable residual disease (MRD) and recently identified tumor genetic subtypes. read more here.
Keywords: residual disease; genetic subtypes; impact minimal; lymphoblastic leukemia ... See more keywords
What is the clinical impact of staging and surveillance PET‐CT scan findings in patients with bone and soft tissue sarcoma?
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Surgical Oncology"
DOI: 10.1002/jso.26789
Abstract: Positron emission tomography‐computerized tomography (PET‐CTs) are becoming increasingly utilized in sarcoma care, workup, and surveillance. This study aimed to describe additional PET‐CT findings as well as subsequent workups and changes in the clinical course due… read more here.
Keywords: pet scan; surveillance; clinical impact; impact staging ... See more keywords
Clinical value of FDG-PET/CT in bacteremia of unknown origin with catalase-negative gram-positive cocci or Staphylococcus aureus
Sign Up to like & getrecommendations! Published in 2019 at "European Journal of Nuclear Medicine and Molecular Imaging"
DOI: 10.1007/s00259-019-04289-5
Abstract: IntroductionBacteremia is associated with high mortality, especially when the site of infection is unknown. While conventional imaging usually focus on specific body parts, FDG-PET/CT visualizes hypermetabolic foci throughout the body.PurposeTo investigate the ability of FDG/PET-CT… read more here.
Keywords: bacteremia unknown; clinical impact; pet; fdg pet ... See more keywords
Encouraging MSK imaging research towards clinical impact is a necessity: opinion paper of the European Society of Musculoskeletal Radiology (ESSR)
Sign Up to like & getrecommendations! Published in 2019 at "European Radiology"
DOI: 10.1007/s00330-019-06218-4
Abstract: AbstractRadiology has not been spared in recent economic crises with a substantial reduction in the turnover of imaging equipment. These problems are exacerbated by increasing demand for healthcare across Europe. Therefore, using existing radiological services… read more here.
Keywords: research; paper; radiology; clinical impact ... See more keywords
Clinical impact of rare variants associated with inherited channelopathies: a 5-year update.
Sign Up to like & getrecommendations! Published in 2021 at "Human genetics"
DOI: 10.1007/s00439-021-02370-4
Abstract: A proper interpretation of the pathogenicity of rare variants is crucial before clinical translation. Ongoing addition of new data may modify previous variant classifications; however, how often a reanalysis is necessary remains undefined. We aimed… read more here.
Keywords: clinical impact; associated inherited; rare variants; inherited channelopathies ... See more keywords
Applying the thresholds for clinical importance for fourteen key domains of the EORTC QLQ-C30: a latent class analysis of cancer survivors
Sign Up to like & getrecommendations! Published in 2021 at "Supportive Care in Cancer"
DOI: 10.1007/s00520-021-06292-9
Abstract: A person’s quality of life is impacted from the beginning of their oncology experience. One of the most common tools to measure quality of life is the EORTC QLQ-C30. The absolute scores it produces can… read more here.
Keywords: cancer; cancer survivors; clinical impact; clinical importance ... See more keywords
Clinical impact of additional therapy for residual pancreatic cancer
Sign Up to like & getrecommendations! Published in 2019 at "Surgery Today"
DOI: 10.1007/s00595-019-01900-y
Abstract: Purpose This study aimed to explore the prognostic significance of the resection margin (R) status of pancreatic ductal adenocarcinoma (PDAC) patients receiving neoadjuvant therapy (NAT) or adjuvant chemotherapy (AC). Methods We retrospectively reviewed 427 consecutive… read more here.
Keywords: therapy; nat group; clinical impact; resection ... See more keywords