Challenges of Francisella classification exemplified by an atypical clinical isolate.
Sign Up to like & getrecommendations! Published in 2018 at "Diagnostic microbiology and infectious disease"
DOI: 10.1016/j.diagmicrobio.2017.11.023
Abstract: The accumulation of sequenced Francisella strains has made it increasingly apparent that the 16S rRNA gene alone is not enough to stratify the Francisella genus into precise and clinically useful classifications. Continued whole-genome sequencing of… read more here.
Keywords: francisella; clinical isolate; challenges francisella; francisella classification ... See more keywords
Ciprofloxacin-Tethered 1,2,3-Triazole Conjugates: New Quinolone Family Compounds to Upgrade Our Antiquated Approach against Bacterial Infections
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DOI: 10.1021/acsomega.1c05303.s001
Abstract: A newer ciprofloxacin series containing 1,2,3-triazole conjugates of ciprofloxacin was designed, synthesized, and well characterized using modern analytical techniques by reacting diversified anilines with ciprofloxacin obtained from ciprofloxacin hydrochloride. The newer conjugates were evaluated for… read more here.
Keywords: compound; ciprofloxacin tethered; clinical isolate; typhi clinical ... See more keywords
Establishment and Characterization of an HBV Viral Spread and Infectious System following Long-Term Passage of an HBV Clinical Isolate in the Primary Human Hepatocyte and Fibroblast Coculture System
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DOI: 10.1128/jvi.00849-22
Abstract: The existing cell culture-based methods to study HBV have limitations and do not allow for viral long-term passage. In this study, an HBV genotype A clinical isolate was subjected to multiple rounds of UV treatment… read more here.
Keywords: long term; system; clinical isolate; passage ... See more keywords
hapE and hmg1 Mutations Are Drivers of cyp51A-Independent Pan-Triazole Resistance in an Aspergillus fumigatus Clinical Isolate
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DOI: 10.1128/spectrum.05188-22
Abstract: Triazole resistance is an important cause of treatment failure and high mortality rates for A. fumigatus human infections. Although Cyp51A-associated mutations are frequently identified as the cause of A. fumigatus triazole resistance, they do not… read more here.
Keywords: clinical isolate; hape hmg1; resistance; triazole resistance ... See more keywords
Proteomic analysis of the colistin-resistant E. coli clinical isolate: Explorations of the resistome.
Sign Up to like & getrecommendations! Published in 2021 at "Protein and peptide letters"
DOI: 10.2174/0929866528666211129095001
Abstract: BACKGROUND Antimicrobial resistance is a worldwide problem after the emergence of colistin resistance since it was the last option left to treat carbapenemase-resistant bacterial infections. The mcr gene and its variants are one of the… read more here.
Keywords: coli clinical; resistance; clinical isolate; colistin ... See more keywords
Characterization of Extracellular Vesicles Secreted by a Clinical Isolate of Naegleria fowleri and Identification of Immunogenic Components within Their Protein Cargo
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DOI: 10.3390/biology11070983
Abstract: Simple Summary Extracellular vesicles are vesicles produced by cells and organisms, capable of developing different functions. In this sense, these vesicles have been involved in communication, in the production of damage during an infection and… read more here.
Keywords: naegleria fowleri; extracellular vesicles; clinical isolate; vesicles secreted ... See more keywords