Clinical Phenotyping of Heart Failure with Biomarkers: Current and Future Perspectives
Sign Up to like & getrecommendations! Published in 2017 at "Current Heart Failure Reports"
DOI: 10.1007/s11897-017-0321-4
Abstract: IntroductionHeart failure (HF) is a complex clinical syndrome with diverse risk factors and etiologies, differing underlying pathophysiology, and large phenotypic heterogeneity.Recent FindingsAdvances in imaging techniques coupled with clinical trials that targeted only in those with… read more here.
Keywords: failure biomarkers; clinical phenotyping; heart failure; phenotyping heart ... See more keywords
First-line genome sequencing is here to stay, but how crucial is clinical phenotyping going to be?
Sign Up to like & getrecommendations! Published in 2022 at "BMJ Case Reports"
DOI: 10.1136/bcr-2021-247238
Abstract: © BMJ Publishing Group Limited 2022. No commercial reuse. See rights and permissions. Published by BMJ. DESCRIPTION With the advancement of costefficient nextgeneration sequencing technology already impacting clinical medicine, one may be led to believe… read more here.
Keywords: genome sequencing; diagnosis; medicine; sequencing stay ... See more keywords
MULTI-PHACET: multidimensional clinical phenotyping of hospitalised acute COPD exacerbations
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DOI: 10.1183/23120541.00198-2021
Abstract: Background The generic term “exacerbation” does not reflect the heterogeneity of acute exacerbations of COPD (AECOPD). We utilised a novel algorithmic strategy to profile exacerbation phenotypes based on underlying aetiologies. Methods Patients hospitalised for AECOPD… read more here.
Keywords: clinical phenotyping; multi phacet; versus; exacerbation ... See more keywords
Personalized Clinical Phenotyping through Systems Medicine and Artificial Intelligence
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Personalized Medicine"
DOI: 10.3390/jpm11040265
Abstract: Personalized Medicine (PM) has shifted the traditional top-down approach to medicine based on the identification of single etiological factors to explain diseases, which was not suitable for explaining complex conditions. The concept of PM assumes… read more here.
Keywords: systems medicine; medicine; clinical phenotyping; artificial intelligence ... See more keywords