Emerging role of exosomes and exosomal microRNA in cancer: pathophysiology and clinical potential
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Cancer Research and Clinical Oncology"
DOI: 10.1007/s00432-021-03534-5
Abstract: Exosomes are extracellular nanometric vesicles used by cells to communicate with each other. They are responsible for many pathological conditions, including tumors by transferring regulatory biomolecules that impact target cell activity. Because of their high… read more here.
Keywords: clinical potential; cancer pathophysiology; role exosomes; exosomes exosomal ... See more keywords
Clinical Potential of Estrogen and Progesterone Receptor Imaging.
Sign Up to like & getrecommendations! Published in 2018 at "PET clinics"
DOI: 10.1016/j.cpet.2018.02.005
Abstract: Molecular imaging using 16α-[18F]fluoro-17β-estradiol (FES) and 18F-fluoro-furanyl-norprogesterone PET can assess in vivo function of steroid hormone receptors in breast cancer. These experimental agents have been tested in many single-center clinical trials and show promise to elucidate… read more here.
Keywords: progesterone receptor; clinical potential; estrogen progesterone; estrogen ... See more keywords
Flavones and flavonols may have clinical potential as CK2 inhibitors in cancer therapy.
Sign Up to like & getrecommendations! Published in 2020 at "Medical hypotheses"
DOI: 10.1016/j.mehy.2020.109723
Abstract: The serine-threonine kinase CK2, which targets over 300 cellular proteins, is overexpressed in all cancers, presumably reflecting its ability to promote proliferation, spread, and survival through a wide range of complementary mechanisms. Via an activating… read more here.
Keywords: flavones flavonols; cancer; ck2 inhibitors; inhibitors cancer ... See more keywords
Clinical Potential of Adrenomedullin Signaling in the Cardiovascular System.
Sign Up to like & getrecommendations! Published in 2023 at "Circulation research"
DOI: 10.1161/circresaha.123.321673
Abstract: Numerous clinical studies have revealed the utility of circulating AM (adrenomedullin) or MR-proAM (mid-regional proAM 45-92) as an effective prognostic and diagnostic biomarker for a variety of cardiovascular-related pathophysiologies. Thus, there is strong supporting evidence… read more here.
Keywords: cardiovascular system; adrenomedullin signaling; potential adrenomedullin; clinical potential ... See more keywords
ERβ in Granulosa Cell Tumors and Its Clinical Potential
Sign Up to like & getrecommendations! Published in 2023 at "Endocrinology"
DOI: 10.1210/endocr/bqad063
Abstract: Abstract Granulosa cell tumors (GCTs) are rare ovarian tumors comprising an adult and a juvenile subtype. They have a generally good prognosis, but the survival rate drastically declines in patients with late-stage or recurring tumors.… read more here.
Keywords: tumors clinical; clinical potential; cell tumors; granulosa cell ... See more keywords
Biomedical Applications of Quantum Dots: Overview, Challenges, and Clinical Potential
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Nanomedicine"
DOI: 10.2147/ijn.s357980
Abstract: Abstract Despite the massive advancements in the nanomedicines and their associated research, their translation into clinically-applicable products is still below promises. The latter fact necessitates an in-depth evaluation of the current nanomedicines from a clinical… read more here.
Keywords: quantum dots; biomedical applications; clinical potential; dots overview ... See more keywords
The OSE complotype and its clinical potential
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.1010893
Abstract: Cellular death, aging, and tissue damage trigger inflammation that leads to enzymatic and non-enzymatic lipid peroxidation of polyunsaturated fatty acids present on cellular membranes and lipoproteins. This results in the generation of highly reactive degradation… read more here.
Keywords: oxidative stress; clinical potential; associated oxidative; mda epitopes ... See more keywords
Clinical potential of tension-lengthening strategies during nerve repair
Sign Up to like & getrecommendations! Published in 2022 at "Neural Regeneration Research"
DOI: 10.4103/1673-5374.322461
Abstract: A (very) brief history of tension in nerve repair: Successful nerve repair is achieved by conveying as many axons successfully to their targets as possible. Typically, this is best achieved through a direct end-to-end repair… read more here.
Keywords: clinical potential; nerve repair; tension lengthening; tension ... See more keywords
Dual role of fucosidase in cancers and its clinical potential
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cancer"
DOI: 10.7150/jca.75840
Abstract: Glycosidases and glycosyltransferases greatly impact malignant phenotype of tumors though genetics and epigenetics mechanisms. As the member of glycoside hydrolase (GH) families 29A, α-L-fucosidases (AFUs) are involved in the hydrolysis of terminal L-fucose residues linked… read more here.
Keywords: clinical potential; fucosidase cancers; role fucosidase; cancers clinical ... See more keywords