Assessment of Clinical Response to Anifrolumab in Patients With Refractory Discoid Lupus Erythematosus.
Sign Up to like & getrecommendations! Published in 2023 at "JAMA dermatology"
DOI: 10.1001/jamadermatol.2023.0175
Abstract: This case series examines the efficacy of anifrolumab as a therapeutic option for patients with lupus erythematosus. read more here.
Keywords: clinical response; patients refractory; anifrolumab patients; response anifrolumab ... See more keywords
Effect of Gram Stain–Guided Initial Antibiotic Therapy on Clinical Response in Patients With Ventilator-Associated Pneumonia
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2022.6136
Abstract: This randomized clinical trial compares the clinical response to Gram stain–guided vs guideline-based antibiotic therapy in patients with ventilator-associated pneumonia. read more here.
Keywords: clinical response; patients ventilator; gram stain; antibiotic therapy ... See more keywords
Clinical response to chemoradiotherapy in esophageal carcinoma is associated with survival and benefit of consolidation chemotherapy
Sign Up to like & getrecommendations! Published in 2020 at "Cancer Medicine"
DOI: 10.1002/cam4.3273
Abstract: Abstract Purpose Few studies have reported the impact of the clinical response of patients with Esophageal Carcinoma to chemoradiotherapy (CRT). Our study examines the association between clinical response and pretreatment variables, survival, patterns of failure,… read more here.
Keywords: response; chemoradiotherapy; consolidation chemotherapy; benefit consolidation ... See more keywords
A prospective study of DAA Effectiveness and Relapse Risk in HCV Cryoglobulinemic Vasculitis by the Italian PITER Cohort.
Sign Up to like & getrecommendations! Published in 2021 at "Hepatology"
DOI: 10.1002/hep.32281
Abstract: BACKGROUND & AIMS Mixed cryoglobulinemia (MC) is the most common Hepatitis C Virus (HCV) extrahepatic manifestation. We aimed to prospectively evaluate the Cryoglobulinemic Vasculitis (CV) clinical profile after a sustained virologic response (SVR) over a… read more here.
Keywords: response; cryoglobulinemic vasculitis; piter cohort; relapse ... See more keywords
Upadacitinib is associated with clinical response and steroid-free remission for children and adolescents with inflammatory bowel disease.
Sign Up to like & getrecommendations! Published in 2024 at "Journal of pediatric gastroenterology and nutrition"
DOI: 10.1002/jpn3.12408
Abstract: OBJECTIVE Upadacitinib, an oral Janus kinase inhibitor (JAKi), is approved for inflammatory bowel disease (IBD) in adults. As on-label use will face significant delay in pediatrics, a real-world understanding of safety and efficacy in children… read more here.
Keywords: clinical response; disease; response; remission ... See more keywords
Cortical Effects of Dopamine Replacement Account for Clinical Response Variability in Parkinson's Disease
Sign Up to like & getrecommendations! Published in 2024 at "Movement Disorders"
DOI: 10.1002/mds.30200
Abstract: Individual variability in clinical response to dopamine replacement therapy (DRT) is a key barrier to efficacious treatment for patients with Parkinson's disease (PD). A better understanding of the neurobiological sources of such interindividual differences is… read more here.
Keywords: clinical response; variability; parkinson disease; dopamine replacement ... See more keywords
Has the therapeutical ceiling been reached in Crohn's disease randomized controlled trials? A systematic review and meta‐analysis
Sign Up to like & getrecommendations! Published in 2023 at "United European Gastroenterology Journal"
DOI: 10.1002/ueg2.12366
Abstract: Abstract Background and Aims The availability of biological agents for inflammatory bowel disease has increased over the past years. In this systematic review and meta‐analysis, we aimed to explore time trends in clinical response and… read more here.
Keywords: clinical remission; clinical response; remission; systematic review ... See more keywords
Absolute number of new lesions on 18F-FDG PET/CT is more predictive of clinical response than SUV changes in metastatic melanoma patients receiving ipilimumab
Sign Up to like & getrecommendations! Published in 2017 at "European Journal of Nuclear Medicine and Molecular Imaging"
DOI: 10.1007/s00259-017-3870-6
Abstract: PurposeEvaluation of response to immunotherapy is a matter of debate. The aim of the present study was to evaluate the response of metastatic melanoma to treatment with ipilimumab by means of 18F-FDG PET/CT, using the… read more here.
Keywords: response; new lesions; fdg pet; 18f fdg ... See more keywords
Impact of clinical response and treatment tolerability on HRQoL in newly diagnosed Philadelphia chromosome-positive acute lymphoblastic leukemia patients treated with ponatinib or imatinib
Sign Up to like & getrecommendations! Published in 2025 at "Annals of Hematology"
DOI: 10.1007/s00277-025-06635-0
Abstract: In the phase 3 PhALLCON trial (NCT03589326), ponatinib demonstrated superior efficacy, patient-reported treatment tolerability, and health-related quality of life (HRQoL) compared to imatinib in adults with newly diagnosed Philadelphia chromosome-positive (Ph+) acute lymphoblastic leukemia (ALL).… read more here.
Keywords: clinical response; ponatinib imatinib; treatment; response ... See more keywords
A retrospective study of the efficacy of sulbactam in the treatment of patients with extensively drug-resistant Acinetobacter baumannii infections
Sign Up to like & getrecommendations! Published in 2024 at "Infection"
DOI: 10.1007/s15010-024-02307-9
Abstract: Sulbactam (SBT) is one of the most significant treatments for patients with extensively drug-resistant Acinetobacter baumannii (XDR-AB). However, the efficacy and safety of SBT and its high dose regimen has not been well documented. This… read more here.
Keywords: clinical response; treatment; sbt; response ... See more keywords
Conserved Interferon-γ Signaling Drives Clinical Response to Immune Checkpoint Blockade Therapy in Melanoma.
Sign Up to like & getrecommendations! Published in 2020 at "Cancer cell"
DOI: 10.1016/j.ccell.2020.08.005
Abstract: We analyze the transcriptome of baseline and on-therapy tumor biopsies from 101 patients with advanced melanoma treated with nivolumab (anti-PD-1) alone or combined with ipilimumab (anti-CTLA-4). We find that T cell infiltration and interferon-γ (IFN-γ) signaling… read more here.
Keywords: checkpoint blockade; immune checkpoint; blockade therapy; response ... See more keywords