Assessment of Clinical Response to Anifrolumab in Patients With Refractory Discoid Lupus Erythematosus.
Sign Up to like & getrecommendations! Published in 2023 at "JAMA dermatology"
DOI: 10.1001/jamadermatol.2023.0175
Abstract: This case series examines the efficacy of anifrolumab as a therapeutic option for patients with lupus erythematosus. read more here.
Keywords: clinical response; patients refractory; anifrolumab patients; response anifrolumab ... See more keywords
Effect of Gram Stain–Guided Initial Antibiotic Therapy on Clinical Response in Patients With Ventilator-Associated Pneumonia
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2022.6136
Abstract: This randomized clinical trial compares the clinical response to Gram stain–guided vs guideline-based antibiotic therapy in patients with ventilator-associated pneumonia. read more here.
Keywords: clinical response; patients ventilator; gram stain; antibiotic therapy ... See more keywords
Clinical response to chemoradiotherapy in esophageal carcinoma is associated with survival and benefit of consolidation chemotherapy
Sign Up to like & getrecommendations! Published in 2020 at "Cancer Medicine"
DOI: 10.1002/cam4.3273
Abstract: Abstract Purpose Few studies have reported the impact of the clinical response of patients with Esophageal Carcinoma to chemoradiotherapy (CRT). Our study examines the association between clinical response and pretreatment variables, survival, patterns of failure,… read more here.
Keywords: response; chemoradiotherapy; consolidation chemotherapy; benefit consolidation ... See more keywords
A prospective study of DAA Effectiveness and Relapse Risk in HCV Cryoglobulinemic Vasculitis by the Italian PITER Cohort.
Sign Up to like & getrecommendations! Published in 2021 at "Hepatology"
DOI: 10.1002/hep.32281
Abstract: BACKGROUND & AIMS Mixed cryoglobulinemia (MC) is the most common Hepatitis C Virus (HCV) extrahepatic manifestation. We aimed to prospectively evaluate the Cryoglobulinemic Vasculitis (CV) clinical profile after a sustained virologic response (SVR) over a… read more here.
Keywords: response; cryoglobulinemic vasculitis; piter cohort; relapse ... See more keywords
Has the therapeutical ceiling been reached in Crohn's disease randomized controlled trials? A systematic review and meta‐analysis
Sign Up to like & getrecommendations! Published in 2023 at "United European Gastroenterology Journal"
DOI: 10.1002/ueg2.12366
Abstract: Abstract Background and Aims The availability of biological agents for inflammatory bowel disease has increased over the past years. In this systematic review and meta‐analysis, we aimed to explore time trends in clinical response and… read more here.
Keywords: clinical remission; clinical response; remission; systematic review ... See more keywords
Absolute number of new lesions on 18F-FDG PET/CT is more predictive of clinical response than SUV changes in metastatic melanoma patients receiving ipilimumab
Sign Up to like & getrecommendations! Published in 2017 at "European Journal of Nuclear Medicine and Molecular Imaging"
DOI: 10.1007/s00259-017-3870-6
Abstract: PurposeEvaluation of response to immunotherapy is a matter of debate. The aim of the present study was to evaluate the response of metastatic melanoma to treatment with ipilimumab by means of 18F-FDG PET/CT, using the… read more here.
Keywords: response; new lesions; fdg pet; 18f fdg ... See more keywords
Conserved Interferon-γ Signaling Drives Clinical Response to Immune Checkpoint Blockade Therapy in Melanoma.
Sign Up to like & getrecommendations! Published in 2020 at "Cancer cell"
DOI: 10.1016/j.ccell.2020.08.005
Abstract: We analyze the transcriptome of baseline and on-therapy tumor biopsies from 101 patients with advanced melanoma treated with nivolumab (anti-PD-1) alone or combined with ipilimumab (anti-CTLA-4). We find that T cell infiltration and interferon-γ (IFN-γ) signaling… read more here.
Keywords: checkpoint blockade; immune checkpoint; blockade therapy; response ... See more keywords
IMUNNOPHENOTYPIC CHANGES IN JMML PATIENTS TREATED WITH 5-AZACITIDINE AND CORRELATION WITH CLINICAL RESPONSE
Sign Up to like & getrecommendations! Published in 2021 at "Hematology, Transfusion and Cell Therapy"
DOI: 10.1016/j.htct.2021.10.488
Abstract: Background 5-azacitidine has been considered to be safe and efficient medication for use as a bridge to hemotopoietic stem cell transplantation in JMML patients. Patients under clinical treatment can be stratified as complete or partial… read more here.
Keywords: patients treated; response; treatment; jmml patients ... See more keywords
Correlation of newer indices of dyssynchrony with clinical response in patients undergoing cardiac resynchronisation therapy
Sign Up to like & getrecommendations! Published in 2021 at "Indian Heart Journal"
DOI: 10.1016/j.ihj.2020.12.011
Abstract: Abstract – The benefits of CRT in select subsets of systolic heart failure patients with LBBB are proven. We prospectively evaluated conventional and newer echocardiographic parameters of left ventricular dyssynchrony in 35 patients who underwent… read more here.
Keywords: response patients; correlation newer; newer indices; indices dyssynchrony ... See more keywords
Prospective evaluation of a clinical response directed pathway for complicated appendicitis.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of pediatric surgery"
DOI: 10.1016/j.jpedsurg.2018.10.082
Abstract: AIM Despite evidence to suggest shorter durations of antibiotics are safe in complicated appendicitis, the practice has not been widely adopted in the UK. Our aim was to determine whether a clinical pathway that tailors… read more here.
Keywords: complicated appendicitis; evaluation clinical; prospective evaluation; appendicitis ... See more keywords
Joining Forces: Improving Clinical Response to Cellular Immunotherapies with Small-Molecule Inhibitors.
Sign Up to like & getrecommendations! Published in 2020 at "Trends in molecular medicine"
DOI: 10.1016/j.molmed.2020.09.005
Abstract: Adoptive T cell therapy (ACT) has emerged as a powerful therapeutic tool against both hematological and virus-associated cancers. However, extension of this success to solid cancers has been challenging owing to intratumoral mechanisms that induce… read more here.
Keywords: forces improving; act; response cellular; joining forces ... See more keywords