Clinical responses in cows vaccinated with a developed prototype killed Staphylococcus aureus mastitis vaccine.
Sign Up to like & getrecommendations! Published in 2018 at "Microbial pathogenesis"
DOI: 10.1016/j.micpath.2018.08.017
Abstract: Mastitis is an inflammatory condition of the udder that occurs as a result of the release of leucocytes into the udder in a response to bacterial invasion. The major causes of mastitis are an array… read more here.
Keywords: mastitis; control; group; significantly different ... See more keywords
Mechanical Power Delivered by Noninvasive Ventilation Contributes to Physio-Anatomical and Clinical Responses to Early Versus Late Proning in COVID-19 Pneumonia.
Sign Up to like & getrecommendations! Published in 2023 at "Critical care medicine"
DOI: 10.1097/ccm.0000000000005915
Abstract: OBJECTIVES To study: 1) the effect of prone position (PP) on noninvasive ventilation (NIV)-delivered mechanical power (MP) and 2) the impact of MP on physio-anatomical and clinical responses to early versus late PP in severe… read more here.
Keywords: anatomical clinical; mechanical power; noninvasive ventilation; clinical responses ... See more keywords
Abstract 4464: Pharmacodynamic and predictive biomarkers of clinical responses to PD-1 inhibitor budigalimab from the first-in-human clinical trial
Sign Up to like & getrecommendations! Published in 2020 at "Immunology"
DOI: 10.1158/1538-7445.am2020-4464
Abstract: Background: Programmed cell death 1 (PD-1) is a receptor upregulated on activated lymphocytes that mediates a dominant-negative checkpoint signal limiting antigen receptor-driven cellular activation. PD-1 immune checkpoint inhibitors have shown durable clinical responses in patients… read more here.
Keywords: clinical trial; inhibitor; hnscc nsclc; pharmacodynamic predictive ... See more keywords
A Pilot Study Investigating Clinical Responses and Biological Pathways of Azelastine/Fluticasone in Nonallergic Vasomotor Rhinitis before and after Cold Dry Air Provocation
Sign Up to like & getrecommendations! Published in 2017 at "International Archives of Allergy and Immunology"
DOI: 10.1159/000478698
Abstract: Background: Nonallergic vasomotor rhinitis (NAVMR) has been considered a diagnosis by exclusion due to unknown mechanisms or lack of diagnostic biomarkers. Methods: To determine clinical responses and biological pathways in NAVMR subjects challenged to cold… read more here.
Keywords: cda; biological pathways; vasomotor rhinitis; visit ... See more keywords
Functional systemic CD4 immunity is required for clinical responses to PD‐L1/PD‐1 blockade therapy
Sign Up to like & getrecommendations! Published in 2019 at "EMBO Molecular Medicine"
DOI: 10.15252/emmm.201910293
Abstract: The majority of lung cancer patients progressing from conventional therapies are refractory to PD‐L1/PD‐1 blockade monotherapy. Here, we show that baseline systemic CD4 immunity is a differential factor for clinical responses. Patients with functional systemic… read more here.
Keywords: functional systemic; cd4 immunity; immunity; systemic cd4 ... See more keywords
Dawn of Monitoring Regulatory T Cells in (Pre-)clinical Studies: Their Relevance Is Slowly Recognised
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Medicine"
DOI: 10.3389/fmed.2020.00091
Abstract: Regulatory T cells (Tregs) have a prominent role in the control of immune homeostasis. Pharmacological impact on their activity or balance with effector T cells could contribute to (impaired) clinical responses or adverse events. Monitoring… read more here.
Keywords: clinical studies; dawn monitoring; regulatory cells; pre clinical ... See more keywords
Differences in Clinical Responses to Ustekinumab Treatment among Body Regions: Results from a Real-World Prospective, Observational, and Multi-Center Study in Korea
Sign Up to like & getrecommendations! Published in 2022 at "Annals of Dermatology"
DOI: 10.5021/ad.2022.34.1.14
Abstract: Background In psoriasis treatment, not all body regions improve simultaneously after clinical interventions. Objective This study was aimed at evaluating clinical responses across body regions, which may differentially influence patient treatment plans. Methods This prospective,… read more here.
Keywords: study; body; lower extremities; body regions ... See more keywords