A Clinical-Scale Microfluidic Respiratory Assist Device with 3D Branching Vascular Networks.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced science"
DOI: 10.1002/advs.202207455
Abstract: Recent global events such as COVID-19 pandemic amid rising rates of chronic lung diseases highlight the need for safer, simpler, and more available treatments for respiratory failure, with increasing interest in extracorporeal membrane oxygenation (ECMO).… read more here.
Keywords: respiratory assist; microfluidic respiratory; assist device; blood ... See more keywords
An Improved Method to Produce Clinical-Scale Natural Killer Cells from Human Pluripotent Stem Cells
Sign Up to like & getrecommendations! Published in 2019 at "Methods in Molecular Biology"
DOI: 10.1007/978-1-4939-9728-2_12
Abstract: Human natural killer (NK) cell-based adoptive anticancer immunotherapy has gained intense interest with many clinical trials actively recruiting patients to treat a variety of both hematological malignancies and solid tumors. Most of these trials use… read more here.
Keywords: clinical scale; stem cells; cell; pluripotent stem ... See more keywords
Cross-cultural adaptation and validation of the Swallowing Disturbance Questionnaire and the Sialorrhea Clinical Scale in Portuguese patients with Parkinson’s disease
Sign Up to like & getrecommendations! Published in 2020 at "Logopedics Phoniatrics Vocology"
DOI: 10.1080/14015439.2020.1792979
Abstract: Abstract Introduction To date, no valid outcome measure has been developed in European Portuguese (EP) to evaluate the Parkinsons’ Disease (PD) patients' (PwP) reports regarding their swallowing disturbances. Objectives The aim of this study was… read more here.
Keywords: disturbance questionnaire; validity; clinical scale; swallowing disturbance ... See more keywords
Process Development for Adoptive Cell Therapy in Academia: A Pipeline for Clinical-Scale Manufacturing of Multiple TCR-T Cell Products
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.896242
Abstract: Cellular immunotherapies based on T cell receptor (TCR) transfer are promising approaches for the treatment of cancer and chronic viral infections. The discovery of novel receptors is expanding considerably; however, the clinical development of TCR-T… read more here.
Keywords: tcr cell; scale manufacturing; cell; tcr ... See more keywords
Pilot Quality-Assurance Study of a Third-Generation Batch-Mode Clinical-Scale Automated Xenon-129 Hyperpolarizer
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27041327
Abstract: We present a pilot quality assurance (QA) study of a clinical-scale, automated, third-generation (GEN-3) 129Xe hyperpolarizer employing batch-mode spin-exchange optical pumping (SEOP) with high-Xe densities (50% natural abundance Xe and 50% N2 in ~2.6 atm… read more here.
Keywords: generation; seop cell; hyperpolarizer; clinical scale ... See more keywords