Navigating Clinical Utilization of Direct-from-Specimen Metagenomic Pathogen Detection: Clinical Applications, Limitations, and Testing Recommendations.
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DOI: 10.1093/clinchem/hvaa183
Abstract: BACKGROUND Metagenomic next generation sequencing (mNGS) is becoming increasingly available for pathogen detection directly from clinical specimens. These tests use target-independent, shotgun sequencing to detect potentially unlimited organisms. The promise of this methodology to aid… read more here.
Keywords: clinical utilization; pathogen; testing recommendations; pathogen detection ... See more keywords
Natural Killer Cells: Development, Maturation, and Clinical Utilization
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DOI: 10.3389/fimmu.2018.01869
Abstract: Natural killer (NK) cells are the predominant innate lymphocyte subsets that mediate anti-tumor and anti-viral responses, and therefore possess promising clinical utilization. NK cells do not express polymorphic clonotypic receptors and utilize inhibitory receptors (killer… read more here.
Keywords: clinical utilization; natural killer; development; killer cells ... See more keywords
Clinical Utilization of the FilmArray Meningitis/Encephalitis (ME) Multiplex Polymerase Chain Reaction (PCR) Assay
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DOI: 10.3389/fneur.2019.00281
Abstract: Objective: To assess the clinical utilization and performance of the FilmArray® Meningitis/Encephalitis (ME) multiplex polymerase chain reaction (PCR) panel in a hospital setting. Background: Rapid diagnosis and treatment of central nervous system (CNS) infections are… read more here.
Keywords: meningitis encephalitis; clinical utilization; encephalitis multiplex; filmarray meningitis ... See more keywords