A Clinically Translatable Ternary Platinum(IV) Prodrug for Synergistically Reversing Drug Resistance .
Sign Up to like & getrecommendations! Published in 2023 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.2c01924
Abstract: Scalable production of a clinically translatable formulation with enhanced therapeutic efficacy against cisplatin-resistant tumors without the use of any clinically unapproved reagents and additional manipulation remains a challenge. For this purpose, we report herein the… read more here.
Keywords: clinically translatable; reversing drug; prodrug; synergistically reversing ... See more keywords
A clinically translatable hyperspectral endoscopy (HySE) system for imaging the gastrointestinal tract
Sign Up to like & getrecommendations! Published in 2019 at "Nature Communications"
DOI: 10.1038/s41467-019-09484-4
Abstract: Hyperspectral imaging (HSI) enables visualisation of morphological and biochemical information, which could improve disease diagnostic accuracy. Unfortunately, the wide range of image distortions that arise during flexible endoscopy in the clinic have made integration of… read more here.
Keywords: translatable hyperspectral; image; clinically translatable; hyperspectral endoscopy ... See more keywords
A clinically translatable kit for MRI/NMI dual-modality nanoprobes based on anchoring group-mediated radiolabeling.
Sign Up to like & getrecommendations! Published in 2023 at "Nanoscale"
DOI: 10.1039/d2nr05988f
Abstract: Magnetic resonance imaging (MRI)/nuclear medicine imaging (NMI) dual-modality imaging based on radiolabeled nanoparticles has been increasingly exploited for accurate diagnosis of tumor and cardiovascular diseases by virtue of high spatial resolution and high sensitivity. However,… read more here.
Keywords: dual modality; nmi dual; clinically translatable; kit ... See more keywords
Mutual impact of clinically translatable near-infrared dyes on photoacoustic image contrast and in vitro photodynamic therapy efficacy (Erratum)
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Biomedical Optics"
DOI: 10.1117/1.jbo.25.6.069802
Abstract: Abstract. The erratum corrects an error in the y-axis labels of Fig. 4 and Fig. S2. read more here.
Keywords: clinically translatable; near infrared; translatable near; infrared dyes ... See more keywords
Clinically translatable cytokine delivery platform for eradication of intraperitoneal tumors
Sign Up to like & getrecommendations! Published in 2022 at "Science Advances"
DOI: 10.1126/sciadv.abm1032
Abstract: Proinflammatory cytokines have been approved by the Food and Drug Administration for the treatment of metastatic melanoma and renal carcinoma. However, effective cytokine therapy requires high-dose infusions that can result in antidrug antibodies and/or systemic… read more here.
Keywords: delivery platform; cytokine delivery; translatable cytokine; clinically translatable ... See more keywords