Clinicopathologic and molecular characterization of melanomas mutated for CTNNB1 and MAPK
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DOI: 10.1007/s00428-021-03119-0
Abstract: Wnt/β-catenin signaling plays crucial roles in melanocyte biology and may be implicated in melanoma progression. In this study, we retrospectively examined a real-life cohort of melanomas mutated for β-catenin (CTNNB1), in association or not with… read more here.
Keywords: melanomas; melanomas mutated; clinicopathologic molecular; ctnnb1 mapk ... See more keywords
Prevalence and clinicopathologic/molecular characteristics of mismatch repair-deficient colorectal cancer in the under-50-year-old Japanese population
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DOI: 10.1007/s00595-017-1486-x
Abstract: PurposeTo clarify the prevalence and clinicopathologic/molecular characteristics of mismatch repair (MMR)-deficient colorectal cancer in the young Japanese population.MethodsImmunohistochemical analyses for MMR proteins (MLH1, MSH2, MSH6, and PMS2) were performed in formalin-fixed paraffin-embedded sections prepared from… read more here.
Keywords: characteristics mismatch; deficient colorectal; prevalence clinicopathologic; molecular characteristics ... See more keywords