An automated platform for lentiviral transduction for HSC gene therapy promotes fitness of hematopoietic stem cells combined with higher transduction efficiency
Sign Up to like & getrecommendations! Published in 2025 at "Blood"
DOI: 10.1182/blood-2025-7837
Abstract: Although therapies for HSC gene therapy have been recently approved (Zynteglo™, Lyfgenia™ and Casgevy®), still certain challenges remain associated with high costs, scalability and safety related to leukemic events. These indicate a need for improved… read more here.
Keywords: transduction; transduction efficiency; clinimacs prodigy; automated platform ... See more keywords
Results of Using Automated Clinimacs Prodigy for CD34 Selection from Mobilized Peripheral Blood Stem Cell Products
Sign Up to like & getrecommendations! Published in 2017 at "Blood"
DOI: 10.1182/blood.v130.suppl_1.3201.3201
Abstract: Cell selection is an important part of graft manipulation for cellular therapies. The CliniMACS Plus system has been used in our laboratory for over 15 years to deplete T-cells from stem cell grafts of the… read more here.
Keywords: cd34; prodigy; selection; clinimacs prodigy ... See more keywords