An overview of cdc2‐like kinase 1 (Clk1) inhibitors and their therapeutic indications
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DOI: 10.1002/med.21928
Abstract: Over the past decade, Clk1 has been identified as a promising target for the treatment of various diseases, in which deregulated alternative splicing plays a role. First small molecules targeting Clk1 are in clinical trials… read more here.
Keywords: like kinase; overview cdc2; clk1; alternative splicing ... See more keywords
Induction of beige‐like adipocyte markers and functions in 3T3‐L1 cells by Clk1 and PKCβII inhibitory molecules
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DOI: 10.1111/jcmm.17345
Abstract: Excessive dietary intake of fat results in its storage in white adipose tissue (WAT). Energy expenditure through lipid oxidation occurs in brown adipose tissue (BAT). Certain WAT depots can undergo a change termed beiging where… read more here.
Keywords: inhibition; pgc1; clk1; clk1 pkc ... See more keywords