Articles with "clk2 blockade" as a keyword



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CLK2 blockade modulates alternative splicing compromising MYC‐driven breast tumors

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Published in 2018 at "EMBO Molecular Medicine"

DOI: 10.15252/emmm.201809213

Abstract: MYC oncogene overexpression/amplification is common in multiple human cancers, in which it regulates proliferation, apoptosis and cell metabolism, among other processes, and its expression associates with poor prognosis. Targeting MYC presents an exciting therapeutic possibility,… read more here.

Keywords: modulates alternative; medicine; myc driven; blockade modulates ... See more keywords