CLK3 Is A Direct Target Of miR-144 And Contributes To Aggressive Progression In Hepatocellular Carcinoma
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DOI: 10.2147/ott.s224527
Abstract: Background Hepatocellular carcinoma (HCC) is the most common type of primary liver cancer with high incidence. The underlying molecular mechanisms of HCC development have been intensively studied. CLK3 (CDC Like Kinase 3) is a nuclear… read more here.
Keywords: expression; hepatocellular carcinoma; hcc; mir 144 ... See more keywords
Research towards selective inhibition of the CLK3 kinase
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DOI: 10.3762/bjoc.21.172
Abstract: The cdc2-like kinases (CLKs), are a family of kinases that attracted recently the interest of scientists due to their significant biological roles, in particular in the regulation of the mRNA splicing process. Among the four… read more here.
Keywords: towards selective; research towards; clk3; selective inhibition ... See more keywords