Articles with "cll like" as a keyword



Lymphoma-like monoclonal B cell lymphocytosis in a patient population: biology, natural evolution, and differences from CLL-like clones

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Published in 2018 at "Annals of Hematology"

DOI: 10.1007/s00277-018-3282-0

Abstract: High-count monoclonal B cell lymphocytosis (MBL) with a chronic lymphocytic leukemia (CLL) phenotype is a well-known entity, featuring 1–4% annual risk of progression towards CLL requiring treatment. Lymphoma-like MBL (L-MBL), on the other hand, remains… read more here.

Keywords: mbl; monoclonal cell; cll like; biology ... See more keywords

Long-term event-free survival in patients with IGHV-mutated high-count monoclonal B-cell lymphocytosis and atypical, non-CLL-like phenotypes

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Published in 2025 at "Blood"

DOI: 10.1182/blood-2025-2112

Abstract: Monoclonal B-cell lymphocytosis (MBL) is a frequent precursor of chronic lymphocytic leukemia (CLL) and among the most common premalignant hematologic conditions. It can be either classified by clone size (low-count, LC-MBL versus high-count, HC-MBL) or… read more here.

Keywords: mbl patients; progression; non cll; cells range ... See more keywords

Acquisition of CLL-like epigenetic and transcriptomic states in low-count MBL

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Published in 2025 at "Blood"

DOI: 10.1182/blood-2025-3876

Abstract: Despite substantial advances in targeted therapies, chronic lymphocytic leukemia (CLL) remains incurable, underscoring the need for strategies to predict or even prevent its development. Low-count (LC-) and high-count (HC-) monoclonal B cell lymphocytosis (MBL) are… read more here.

Keywords: analysis; cll; cell; mbl cll ... See more keywords

Characterizing Features of Human Circulating B Cells Carrying CLL-Like Stereotyped Immunoglobulin Rearrangements

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Published in 2022 at "Frontiers in Oncology"

DOI: 10.3389/fonc.2022.894419

Abstract: Chronic Lymphocytic Leukemia (CLL) is characterized by the accumulation of monoclonal CD5+ B cells with low surface immunoglobulins (IG). About 40% of CLL clones utilize quasi-identical B cell receptors, defined as stereotyped BCR. CLL-like stereotyped-IG… read more here.

Keywords: cell subpopulations; cll stereotyped; like stereotyped; cll like ... See more keywords