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   Articles with "cll patients" as a keyword



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Outcomes in CLL patients with NOTCH1 regulatory pathway mutations

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recommendations! Published in 2021 at "American Journal of Hematology"

DOI: 10.1002/ajh.26140

Abstract: All authors made substantial contributions to the (a) conception or design of the work; or the acquisition, analysis, or interpretation of data for the work; and (b) drafting the work or revising it critically for… read more here.

Keywords: patients notch1; work; notch1 regulatory; regulatory pathway ... See more keywords
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Survival of patients with chronic lymphocytic leukemia before and after the introduction of chemoimmunotherapy in Germany

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recommendations! Published in 2021 at "Blood Cancer Journal"

DOI: 10.1038/s41408-021-00556-7

Abstract: Chronic lymphocytic leukemia (CLL) is the most common leukemia of adults in western countries. Therapy is indicated in symptomatic and advanced stages and has changed fundamentally since 2010 when rituximab, an anti-CD20 antibody, has been… read more here.

Keywords: cll; lymphocytic leukemia; chronic lymphocytic; leukemia ... See more keywords
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Real Life Use of Bendamustine Plus Rituximab Versus Chlorambucil Plus Rituximab As Front-Line Therapy for Elderly CLL Patients. Retrospective Multicenter Study in the Lazio Region

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recommendations! Published in 2018 at "Blood"

DOI: 10.1182/blood-2018-99-119408

Abstract: Introduction. Elderly patients with chronic lymphocytic leukemia (CLL) are often treated with chemoimmunotherapeutic regimens. Because of ineligibility for Fludarabine-based protocol, Bendamustine plus Rituximab (B-R) or Chlorambucil plus Rituximab (Chl-R) are the common preferred schemes, chosen… read more here.

Keywords: response; group; study; chl ... See more keywords
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Alterations of Gut Microbiome in Untreated Chronic Lymphocytic Leukemia (CLL); Future Therapeutic Potentials

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recommendations! Published in 2019 at "Blood"

DOI: 10.1182/blood-2019-121643

Abstract: Introduction: Gut dysbiosis is an imbalance of the gut microbiome. The presence of dysbiosis can be a cause of systemic inflammation in the body or can be a contributing factor to it. Chronic systemic inflammation… read more here.

Keywords: dysbiosis; gut dysbiosis; cll; inflammation ... See more keywords
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Characteristics of Mantle Cell Lymphoma (MCL) and Chronic Lymphocytic Leukemia (CLL) Patients Treated with Acalabrutinib in a Real World Setting in the United States

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recommendations! Published in 2019 at "Blood"

DOI: 10.1182/blood-2019-122109

Abstract: Introduction Acalabrutinib was approved by the US Food and Drug Administration on October 31, 2017 for patients with MCL who have progressed on at least one prior therapy and is currently being evaluated in phase… read more here.

Keywords: mcl; cll; real world; cll patients ... See more keywords
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Evaluation of the International Prognostic Index for Chronic Lymphocytic Leukemia (CLL-IPI) and Validation of a Proposed Novel Risk Model (BALL Score) in Real-World Relapsed/Refractory (R/R) CLL Patients Receiving Idelalisib and Rituximab

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recommendations! Published in 2019 at "Blood"

DOI: 10.1182/blood-2019-126717

Abstract: The CLL-IPI score, which combines genetic, biochemical, and clinical parameters, represents a simple worldwide model able to refine risk stratification for CLL patients. This score, developed in the era of chemo-immunotherapy, has not been gauged… read more here.

Keywords: cll; risk; cll ipi; ball score ... See more keywords
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Prognostic significance of microRNA 17–92 cluster expression in Egyptian chronic lymphocytic leukemia patients

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recommendations! Published in 2021 at "Journal of the Egyptian National Cancer Institute"

DOI: 10.1186/s43046-021-00097-x

Abstract: Abnormal expression patterns of microRNAs (miRs) play an important role in the development and progression of malignancy. Identification of the clinical significance and prognostic value of these small molecules in chronic lymphocytic leukemia (CLL); a… read more here.

Keywords: correlation; expression; cluster; cll patients ... See more keywords
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Clinical and demographic characteristics of CLL patients receiving first-line bendamustine plus rituximab using the Flatiron Health database.

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recommendations! Published in 2017 at "Journal of Clinical Oncology"

DOI: 10.1200/jco.2017.35.15_suppl.e19010

Abstract: e19010Background: Chronic lymphocytic leukemia (CLL) is the most common type of leukemia in the Western world, with 20,110 new cases estimated for 2017 in the US alone. Combination therapy with ben... read more here.

Keywords: receiving first; characteristics cll; patients receiving; demographic characteristics ... See more keywords
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Response to Comment by Amato T. et al.

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recommendations! Published in 2019 at "Haematologica"

DOI: 10.3324/haematol.2019.224303

Abstract: We thank the authors for their interest in our Editorial. With their letter, they point to the relevance of IGHV analysis in chronic lymphocytic leukemia (CLL) patients in the context of different ethnic groups other… read more here.

Keywords: african cll; cll; among african; american cll ... See more keywords
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The PI3K∂-Selective Inhibitor Idelalisib Induces T- and NK-Cell Dysfunction Independently of B-Cell Malignancy-Associated Immunosuppression

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recommendations! Published in 2021 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2021.608625

Abstract: B-cell receptors, multiple receptor tyrosine kinases, and downstream effectors are constitutively active in chronic lymphocytic leukemia (CLL) B cells. Activation of these pathways results in resistance to apoptosis and enhanced survival of the leukemic cells.… read more here.

Keywords: selective inhibitor; idelalisib; cll patients; cell malignancy ... See more keywords
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Distinct Age-Related Clinical Features and Risk Assessment in Chinese With Chronic Lymphocytic Leukemia

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recommendations! Published in 2022 at "Frontiers in Oncology"

DOI: 10.3389/fonc.2022.885150

Abstract: The biological and clinical features of chronic lymphocytic leukemia (CLL) exhibited profound heterogeneity across Chinese and patients of predominately European descent. However, the age-related peculiarities and risk assessment of Chinese CLL patients remained ill-defined. The… read more here.

Keywords: cll patients; chronic lymphocytic; age; risk assessment ... See more keywords