Articles with "cln" as a keyword



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Impact of nodal status in determining multimodal treatment strategies in non-cardia gastric cancer.

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Published in 2023 at "Journal of surgical oncology"

DOI: 10.1002/jso.27297

Abstract: BACKGROUND Patients with resectable noncardia gastric cancer may be subjected to perioperative chemotherapy (PEC), postoperative chemoradiation (POCR), or postoperative chemotherapy (POC). We analyzed these treatment strategies to determine optimal therapy based on nodal status. METHOD… read more here.

Keywords: poc; cln; pocr; gastric cancer ... See more keywords
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Clinical value of CT-P13 trough levels, an infliximab biosimilar, in the management of inflammatory bowel disease

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Published in 2020 at "Medicina Clinica"

DOI: 10.1016/j.medcle.2019.07.012

Abstract: Abstract Introduction CT-P13 is a biosimilar drug of infliximab (IFX), effective in patients with inflammatory bowel disease (IBD). The monitoring of levels of IFX and anti-IFX antibodies is now considered part of the integral management.… read more here.

Keywords: week; response; disease; management ... See more keywords
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Application of salt engineering to reduce/mask bitter taste of clindamycin

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Published in 2019 at "Drug Development and Industrial Pharmacy"

DOI: 10.1080/03639045.2019.1672715

Abstract: Abstract Palatability of a formulation is one of the primary requirements for therapeutic compliance in children. Clindamycin (CLN) often prescribed to children to treat various infections. However, it has a bitter taste and bad smell.… read more here.

Keywords: salt; cln cya; salt cln; bitter taste ... See more keywords
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Recent insights into the networking of CLN genes and proteins in mammalian cells

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Published in 2023 at "Journal of Neurochemistry"

DOI: 10.1111/jnc.15822

Abstract: Ceroid lipofuscinosis neuronal (CLN) genes encode 13 proteins that localize throughout the endomembrane system to regulate a variety of cellular processes. In humans, mutations in CLN genes cause a devastating form of neurodegeneration called neuronal… read more here.

Keywords: cln; genes proteins; disease; mammalian cells ... See more keywords
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CARMUSTINE LOADED LACTOFERRIN NANOPARTICLES DEMONSTRATES AN ENHANCED ANTIPROLIFERATIVE ACTIVITY AGAINST GLIOBLASTOMA IN VITRO

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Published in 2018 at "International Journal of Applied Pharmaceutics"

DOI: 10.22159/ijap.2018v10i6.28004

Abstract: Objective: Despite sophisticated treatment regimens, there is no significant improvement in the mortality rates of glioblastoma due to insufficient dosage delivery, reoccurrence of tumors, higher systemic toxicity, etc. Since brain endothelial cells and glioblastoma cells… read more here.

Keywords: carmustine loaded; glioblastoma; drug; carmustine ... See more keywords
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Training method for animal-based measures in dairy cattle welfare assessments.

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Published in 2018 at "Journal of dairy science"

DOI: 10.3168/jds.2018-14469

Abstract: Quantitative assessments of animal welfare are increasingly being used in the dairy industry. It is important to have good precision and accuracy within and among assessors. This study explored the effectiveness of a 3-d training… read more here.

Keywords: agreement; score; bcs; animal based ... See more keywords
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Activation of Mast Cells Promote Plasmodium berghei ANKA Infection in Murine Model

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Published in 2019 at "Frontiers in Cellular and Infection Microbiology"

DOI: 10.3389/fcimb.2019.00322

Abstract: Malaria, a mosquito-borne infectious disease, is a severe health problem worldwide. As reported, some anti-malarial drugs with anti-parasitic properties also block mast cells (MCs) activities. It is hypothesized that MCs activity may be correlated with… read more here.

Keywords: mast cells; berghei anka; infection; plasmodium berghei ... See more keywords
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Novel Lysosome-Targeting Fluorescence Off-On Photosensitizer for Near-Infrared Hypoxia Imaging and Photodynamic Therapy In Vitro and In Vivo

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Published in 2022 at "Molecules"

DOI: 10.3390/molecules27113457

Abstract: Photodynamic therapy (PDT) has emerged as a new antitumor modality. Hypoxia, a vital characteristic of solid tumors, can be explored to stimulate the fluorescence response of photosensitizers (PSs). Considering the characteristics of PDT, the targeting… read more here.

Keywords: cln; near infrared; photodynamic therapy; response ... See more keywords