SOX2-Dependent Transcription in Clock Neurons Promotes the Robustness of the Central Circadian Pacemaker.
Sign Up to like & getrecommendations! Published in 2019 at "Cell reports"
DOI: 10.1016/j.celrep.2019.02.068
Abstract: Clock neurons within the mammalian suprachiasmatic nuclei (SCN) encode circadian time using interlocked transcription-translation feedback loops (TTFLs) that drive rhythmic gene expression. However, the contributions of other transcription factors outside of the circadian TTFLs to… read more here.
Keywords: clock; transcription; scn neurons; sox2 dependent ... See more keywords
Modulation of miR-210 alters phasing of circadian locomotor activity and impairs projections of PDF clock neurons in Drosophila melanogaster
Sign Up to like & getrecommendations! Published in 2018 at "PLoS Genetics"
DOI: 10.1371/journal.pgen.1007500
Abstract: Single microRNAs are usually associated with hundreds of putative target genes that can influence multiple phenotypic traits in Drosophila, ranging from development to behaviour. We investigated the function of Drosophila miR-210 in circadian behaviour by… read more here.
Keywords: clock neurons; locomotor activity; clock; mir 210 ... See more keywords
Circadian Neuropeptide-Expressing Clock Neurons as Regulators of Long-Term Memory: Molecular and Cellular Perspectives
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Molecular Neuroscience"
DOI: 10.3389/fnmol.2022.934222
Abstract: The neuropeptide pigment-dispersing factor (Pdf) is critically involved in the regulation of circadian rhythms in various insects. The function of Pdf in circadian rhythms has been best studied in the fruitfly, i.e., Drosophila melanogaster. Drosophila… read more here.
Keywords: pdf; long term; term memory; memory ... See more keywords
The Neuronal Circuit of the Dorsal Circadian Clock Neurons in Drosophila melanogaster
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2022.886432
Abstract: Drosophila’s dorsal clock neurons (DNs) consist of four clusters (DN1as, DN1ps, DN2s, and DN3s) that largely differ in size. While the DN1as and the DN2s encompass only two neurons, the DN1ps consist of ∼15 neurons,… read more here.
Keywords: circuit dorsal; dns; neuronal circuit; clock neurons ... See more keywords
Norpa Signalling and the Seasonal Circadian Locomotor Phenotype in Drosophila
Sign Up to like & getrecommendations! Published in 2020 at "Biology"
DOI: 10.3390/biology9060130
Abstract: In this paper, we review the role of the norpA-encoded phospholipase C in light and thermal entrainment of the circadian clock in Drosophila melanogaster. We extend our discussion to the role of norpA in the… read more here.
Keywords: phenotype; clock; locomotor; drosophila ... See more keywords