Lanthanum nitrate inhibits adipogenesis in 3T3‐L1 preadipocytes with a disorder of mitotic clonal expansion process
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Applied Toxicology"
DOI: 10.1002/jat.4391
Abstract: Lanthanum (La) as a rare earth element is widely used in agriculture, industry, and medicine. It has been suggested in several studies that La might influence glycolipid metabolism in vivo. In this study, we used… read more here.
Keywords: mitotic clonal; clonal expansion; 3t3 preadipocytes; lanthanum ... See more keywords
Telomere-length dependent T-cell clonal expansion: A model linking ageing to COVID-19 T-cell lymphopenia and mortality
Sign Up to like & getrecommendations! Published in 2022 at "EBioMedicine"
DOI: 10.1016/j.ebiom.2022.103978
Abstract: Background Severe COVID-19 T-cell lymphopenia is more common among older adults and entails poor prognosis. Offsetting the decline in T-cell count during COVID-19 demands fast and massive T-cell clonal expansion, which is telomere length (TL)-dependent.… read more here.
Keywords: cell clonal; covid cell; clonal expansion; cell ... See more keywords
Clonal expansion across the seas as seen through CPLP-TB database: A joint effort in cataloguing Mycobacterium tuberculosis genetic diversity in Portuguese-speaking countries
Sign Up to like & getrecommendations! Published in 2019 at "Infection, Genetics and Evolution"
DOI: 10.1016/j.meegid.2018.03.011
Abstract: Tuberculosis (TB) remains a major health problem within the Community of Portuguese Language Speaking Countries (CPLP). Despite the marked variation in TB incidence across its member-states and continued human migratory flux between countries, a considerable… read more here.
Keywords: speaking countries; tuberculosis; expansion across; clonal expansion ... See more keywords
QUANTITATIVE ANALYSIS OF THE POTENTIAL ROLE OF BASAL CELL HYPERPLASIA IN THE RELATIONSHIP BETWEEN CLONAL EXPANSION AND RADON CONCENTRATION.
Sign Up to like & getrecommendations! Published in 2019 at "Radiation protection dosimetry"
DOI: 10.1093/rpd/ncy302
Abstract: Applying the two-stage clonal expansion model to epidemiology of lung cancer among uranium miners, it has been revealed that radon acts as a promoting agent facilitating the clonal expansion of already mutated cells. Clonal expansion… read more here.
Keywords: expansion rate; rate; clonal expansion; cell ... See more keywords
The “escape” model: a versatile mechanism for clonal expansion
Sign Up to like & getrecommendations! Published in 2019 at "British Journal of Haematology"
DOI: 10.1111/bjh.15111
Abstract: ciation of ofatumumab, a human monoclonal CD20 antibody in patients with relapsed or refractory chronic lymphocytic leukemia: a phase 1-2 study. British Journal of Haematology, 150, 58–71. Korycka-Wołowiec, A., Wołowiec, D. & Robak, T. (2015)… read more here.
Keywords: escape model; versatile mechanism; mechanism clonal; model versatile ... See more keywords
Chrysanthemum indicum suppresses adipogenesis by inhibiting mitotic clonal expansion in 3T3-L1 preadipocytes.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of food biochemistry"
DOI: 10.1111/jfbc.13896
Abstract: Herbs have been of interest to treat diseases, including obesity, owing to their various bioactive constituents that exhibit therapeutic and prophylactic properties. The present study examined the anti-adipogenic effects and mechanisms of Chrysanthemum indicum aqueous… read more here.
Keywords: 3t3 preadipocytes; clonal expansion; cae; mitotic clonal ... See more keywords
Genome Dynamics of Vibrio cholerae Isolates Linked to Seasonal Outbreaks of Cholera in Dhaka, Bangladesh
Sign Up to like & getrecommendations! Published in 2020 at "mBio"
DOI: 10.1128/mbio.03339-19
Abstract: The switching of serotype from Ogawa to Inaba and back to Ogawa has been observed temporally in Vibrio cholerae O1, which is responsible for endemic cholera in Bangladesh. The serospecificity is key for effective intervention… read more here.
Keywords: genome; vibrio cholerae; inaba; serotype ... See more keywords
Emerging Concepts of Vascular Cell Clonal Expansion in Atherosclerosis
Sign Up to like & getrecommendations! Published in 2022 at "Arteriosclerosis, Thrombosis, and Vascular Biology"
DOI: 10.1161/atvbaha.121.316093
Abstract: Clonal expansion is a process that can drive pathogenesis in human diseases, with atherosclerosis being a prominent example. Despite advances in understanding the etiology of atherosclerosis, clonality studies of vascular cells remain in an early… read more here.
Keywords: atherosclerosis; emerging concepts; concepts vascular; vascular cell ... See more keywords
Clonal Expansion of Endothelial Cells Contributes to Ischemia-Induced Neovascularization
Sign Up to like & getrecommendations! Published in 2018 at "Circulation Research"
DOI: 10.1161/circresaha.117.312310
Abstract: Rationale: Vascularization is critical to maintain organ function. Although many molecular pathways were shown to control vessel growth, the genuine process of capillary formation under different conditions is unclear. Objective: Here, we elucidated whether clonal… read more here.
Keywords: expansion; neovascularization; endothelial cells; clonal expansion ... See more keywords
RNA splicing factor Rbm25 underlies heterogeneous preleukemic clonal expansion in mice.
Sign Up to like & getrecommendations! Published in 2023 at "Blood"
DOI: 10.1182/blood.2023019620
Abstract: Clonal expansion sets the stage for cancer genesis by allowing for the accumulation of molecular alterations. While genetic mutations that induce clonal expansion and malignancy, such as Tet2, have been identified, these mutations are also… read more here.
Keywords: rna splicing; clonal expansion; preleukemic clonal; factor ... See more keywords
T-cell lymphoma secondary to checkpoint inhibitor (CPI) used for other malignancies.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2019.37.8_suppl.88
Abstract: 88 Background: Wartewig et al. (Nature 2017) proved in a preclinical mouse model that anti-PD1 therapy could cause T-cell lymphoma. T-cell lymphoma as an adverse event of CPIs has never been reported. A 75-year-old male… read more here.
Keywords: cell lymphoma; cpi; lymphoma secondary; cell ... See more keywords