Abstract 3124: Identification of sub-clonal loss of heterozygosity (LOH) in glioblastomas analyzed with spatial transcriptomics
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DOI: 10.1158/1538-7445.am2023-3124
Abstract: We propose a method to leverage spatial transcriptomics and bioinformatic analysis to identify sub-clonal loss of heterozygosity that could otherwise be missed by standard bulk sequencing in glioblastoma tumors. Glioblastomas are highly invasive and aggressive… read more here.
Keywords: loss heterozygosity; spatial transcriptomics; sub clonal; clonal loss ... See more keywords