Bone marrow clonal hematopoiesis is highly prevalent in blastic plasmacytoid dendritic cell neoplasm and frequently sharing a clonal origin in elderly patients
Sign Up to like & getrecommendations! Published in 2022 at "Leukemia"
DOI: 10.1038/s41375-022-01538-9
Abstract: Myelodysplastic syndrome (MDS) and chronic myelomonocytic leukemia (CMML) are reported in up to 20% patients with blastic plasmacytoid dendritic cell neoplasm (BPDCN), where a shared clonal origin is shown in individual case studies. In this… read more here.
Keywords: clonal origin; dendritic cell; blastic plasmacytoid; cell ... See more keywords
Common clonal origin of conventional T cells and induced regulatory T cells in breast cancer patients
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DOI: 10.1038/s41467-021-21297-y
Abstract: Regulatory CD4+ T cells (Treg) prevent tumor clearance by conventional T cells (Tconv) comprising a major obstacle of cancer immune-surveillance. Hitherto, the mechanisms of Treg repertoire formation in human cancers remain largely unclear. Here, we… read more here.
Keywords: conventional cells; clonal origin; breast cancer; cancer ... See more keywords
Identifying Clonal Origin of Multifocal Hepatocellular Carcinoma and Its Clinical Implications
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DOI: 10.14309/ctg.0000000000000006
Abstract: Hepatocellular carcinoma (HCC) is characterized by high prevalence of multifocality. Multifocal HCC can arise synchronously or metachronously either from intrahepatic metastasis (IM) or multicentric occurrence (MO). To date, there have been no established criteria to… read more here.
Keywords: hepatocellular carcinoma; hcc; clonal origin; multifocal hcc ... See more keywords
Identifying the clonal origin of synchronous multifocal tumors in the hepatobiliary and pancreatic system using multi-omic platforms
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DOI: 10.18632/oncotarget.14018
Abstract: Synchronous multifocal tumors often pose a diagnostic challenge for oncologists. The purpose of this study was to determine the clonal origin and metastatic relationship of synchronous multifocal tumors in the hepatobiliary and pancreatic system using… read more here.
Keywords: multifocal tumors; clonal origin; synchronous multifocal; cancer ... See more keywords