T-Cell Receptor Gene Rearrangement Clonality, Flow Cytometry Status, and Associated Outcomes in Early-Stage Cutaneous T-Cell Lymphoma.
Sign Up to like & getrecommendations! Published in 2021 at "JAMA dermatology"
DOI: 10.1001/jamadermatol.2021.2191
Abstract: Importance The prognostic significance of clonal T-cell receptor (TCR) rearrangement or low-level blood involvement as assessed by flow cytometry for patients with early-stage cutaneous T-cell lymphoma (CTCL) is not clear. Objective To assess the association… read more here.
Keywords: cytometry; early stage; clonality; flow cytometry ... See more keywords
Revealing clonality and subclonality of driver genes for clinical survival benefits in breast cancer
Sign Up to like & getrecommendations! Published in 2019 at "Breast Cancer Research and Treatment"
DOI: 10.1007/s10549-019-05153-8
Abstract: PurposeGenomic studies have revealed that genomic aberrations play important roles in the progression of this disease. The aim of this study was to evaluate the associations between clinical survival outcomes of the clonality and subclonality… read more here.
Keywords: clonality; driver genes; survival; breast cancer ... See more keywords
Variable clonality and genetic structure among disjunct populations of Banksia mimica
Sign Up to like & getrecommendations! Published in 2020 at "Conservation Genetics"
DOI: 10.1007/s10592-020-01288-0
Abstract: Various factors influence patterns of genetic diversity within and between populations that are important considerations for plant conservation. Both clonality and population genetic differentiation are key factors informing conservation actions, especially for rare species. Banksia… read more here.
Keywords: genetic structure; banksia mimica; genetic differentiation; clonality ... See more keywords
A high-throughput detection method for the clonality of Human T-cell leukemia virus type-1-infected cells in vivo
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Hematology"
DOI: 10.1007/s12185-020-02935-5
Abstract: Approximately 10–20 million of Human T-cell leukemia virus type-1 (HTLV-1)-infected carriers have been previously reported, and approximately 5% of these carriers develop adult T-cell leukemia/lymphoma (ATL) with a characteristic poor prognosis. In Japan, Southern blotting… read more here.
Keywords: cell leukemia; clonality; method; infected cells ... See more keywords
Clinical utility of chromosomal microarray in establishing clonality and high risk features in patients with Richter transformation.
Sign Up to like & getrecommendations! Published in 2021 at "Cancer genetics"
DOI: 10.1016/j.cancergen.2021.10.003
Abstract: Richter transformation (RT) refers to the development of an aggressive lymphoma in patients with pre-existing chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL). It carries a poor prognosis secondary to poor response to therapy or rapid disease… read more here.
Keywords: patients richter; chromosomal microarray; transformation; richter transformation ... See more keywords
Whole body clonality analysis in an aggressive STLV-1 associated leukemia (ATLL) reveals an unexpected clonal complexity.
Sign Up to like & getrecommendations! Published in 2017 at "Cancer letters"
DOI: 10.1016/j.canlet.2016.12.022
Abstract: HTLV-1 causes Adult T cell Leukemia/Lymphoma (ATLL) in humans. We describe an ATL-like disease in a 9 year-old female baboon naturally infected with STLV-1 (the simian counterpart of HTLV-1), with a lymphocyte count over 1010/L,… read more here.
Keywords: clonal complexity; atll; clonality; stlv ... See more keywords
Validation and interpretation of IGH and TCR clonality testing by Ion Torrent S5 NGS for diagnosis and disease monitoring in B and T cell cancers
Sign Up to like & getrecommendations! Published in 2020 at "Practical Laboratory Medicine"
DOI: 10.1016/j.plabm.2020.e00191
Abstract: Cancers of B and T lymphocytes are the most common hematologic malignancies in the US. Molecular assays for assessing clonal rearrangements of the immunoglobulin receptor (IGH) and T-cell receptor (TCR), commonly referred to as B-… read more here.
Keywords: disease monitoring; clonality; ion; cell ... See more keywords
PCR-based clonality analysis of antigen receptor gene rearrangements in canine cutaneous plasmacytoma.
Sign Up to like & getrecommendations! Published in 2018 at "Veterinary journal"
DOI: 10.1016/j.tvjl.2018.09.010
Abstract: Plasmacytomas are discrete, B cell-derived, round cell tumours that sometimes are difficult to distinguish from canine cutaneous histiocytomas or T cell lymphosarcomas (lymphomas). Diagnosis of plasmacytomas relies on morphological observations and immunohistochemistry for multiple myeloma… read more here.
Keywords: canine cutaneous; analysis; plasmacytomas; clonality analysis ... See more keywords
Artificial selection optimizes clonality in chaya (Cnidoscolus aconitifolius).
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DOI: 10.1038/s41598-021-00592-0
Abstract: The clonal propagation of crops offers several advantages to growers, such as skipping the juvenile phase, faster growth, and reduced mortality. However, it is not known if the wild ancestors of most clonal crops have… read more here.
Keywords: artificial selection; cnidoscolus aconitifolius; clonality; chaya cnidoscolus ... See more keywords
Utility of a Simple and Robust Flow Cytometry Assay for Rapid Clonality Testing in Mature Peripheral T-Cell Lymphomas
Sign Up to like & getrecommendations! Published in 2019 at "American Journal of Clinical Pathology"
DOI: 10.1093/ajcp/aqy173
Abstract: OBJECTIVES Flow cytometry immunophenotyping is limited by poor resolution of T-cell clones. A newly described antibody was recently used to distinguish normal peripheral blood T cells from malignant T-cell clones. Here, we evaluate this antibody… read more here.
Keywords: clonality; flow cytometry; mature peripheral; cell ... See more keywords
Plant clonality in a soil-impoverished open ecosystem: insights from southwest Australian shrublands.
Sign Up to like & getrecommendations! Published in 2022 at "Annals of botany"
DOI: 10.1093/aob/mcac131
Abstract: BACKGROUND AND AIMS Clonality is a key life history strategy promoting on-spot persistence, space occupancy, resprouting after disturbance and resource storage, sharing and foraging. These functions provided by clonality can be advantageous under different environmental… read more here.
Keywords: southwest australian; abundance; clonality; plant ... See more keywords