Clopidogrel and aspirin after ischemic stroke or transient ischemic attack: an updated systematic review and meta-analysis of randomized clinical trials
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Thrombosis and Thrombolysis"
DOI: 10.1007/s11239-018-1786-z
Abstract: Recurrent stroke is common immediately following a transient ischemic attack (TIA) or ischemic stroke. Dual antiplatelet therapy (DAPT) with clopidogrel and aspirin may provide greater protection against subsequent stroke than monotherapy. Electronic databases were searched… read more here.
Keywords: ischemic stroke; ischemic attack; randomized clinical; clopidogrel aspirin ... See more keywords
Pharmacodynamic effects of a new fixed-dose clopidogrel–aspirin combination compared with separate administration of clopidogrel and aspirin in patients treated with coronary stents: The ACCEL-COMBO trial
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DOI: 10.1080/09537104.2016.1206197
Abstract: Abstract Dual antiplatelet therapy (DAPT) with clopidogrel and aspirin is a widely prescribed regimen to prevent ischemic events in patients undergoing percutaneous coronary intervention (PCI). A fixed-dose combination (FDC) capsule (HCP0911) has been developed to… read more here.
Keywords: combination; clopidogrel; patients treated; treatment ... See more keywords
E-072 Use of eptifibatide as an alternative to preoperative standard dual antiplatelet therapy load for pipeline intracranial aneurysm flow diversion
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DOI: 10.1136/neurintsurg-2017-snis.144
Abstract: Introduction Intracranial aneurysm flow diversion using the Pipeline Embolization Device (PED) has become a common mode of aneurysm treatment. Standard practice involves preoperative loading of a dual antiplatelet (DUAP) regimen that most commonly consists of… read more here.
Keywords: flow diversion; pipeline; antiplatelet; dual antiplatelet ... See more keywords
Risks and benefits of clopidogrel–aspirin in minor stroke or TIA
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DOI: 10.1212/wnl.0000000000003941
Abstract: Objective: To investigate the short-term time course risks and benefits of clopidogrel with aspirin in minor ischemic stroke or TIA. Methods: Data were derived from the Clopidogrel in High-Risk Patients with Acute Nondisabling Cerebrovascular Events… read more here.
Keywords: stroke tia; risk; risks benefits; clopidogrel aspirin ... See more keywords
Ticagrelor Aspirin vs Clopidogrel Aspirin in CYP2C19 Loss-of-Function Carriers With Minor Stroke or TIA Stratified by Risk Profile
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DOI: 10.1212/wnl.0000000000201454
Abstract: Background and Objective Genotype data of the Clopidogrel with Aspirin in Acute Minor Stroke or Transient Ischemic Attack (CHANCE) trial showed that efficacy of clopidogrel aspirin depended on CYP2C19 genotype and risk profile. A stratification… read more here.
Keywords: clopidogrel aspirin; ticagrelor aspirin; risk; aspirin ... See more keywords
Ticagrelor–Aspirin Versus Clopidogrel–Aspirin Among CYP2C19 Loss-of-Function Carriers With Minor Stroke or Transient Ischemic Attack in Relation to Renal Function: A Post Hoc Analysis of the CHANCE-2 Trial
Sign Up to like & getrecommendations! Published in 2022 at "Annals of Internal Medicine"
DOI: 10.7326/m22-1667
Abstract: BACKGROUND Evidence on the risk-benefit ratio of dual antiplatelet therapies among patients with stroke and impaired renal function is limited and inconsistent. OBJECTIVE To investigate the effect of renal function on the efficacy and safety… read more here.
Keywords: ticagrelor aspirin; function; clopidogrel aspirin; renal function ... See more keywords