ABCB1 polymorphism in clopidogrel-treated Montenegrin patients
Sign Up to like & getrecommendations! Published in 2021 at "Open Life Sciences"
DOI: 10.1515/biol-2021-0017
Abstract: Abstract Clopidogrel is an antiplatelet drug that displays significant interindividual variability in treatment response. Its bioavailability depends on the function of P-glycoprotein (P-gp), which is coded by a highly polymorphic ABCB1 gene. Thus, the aim… read more here.
Keywords: polymorphism clopidogrel; clopidogrel efficacy; safety;
Prevalence of CYP2C9 and CYP2C19 variants and the impact on clopidogrel efficacy in patients having CYPC19*2 variant
Sign Up to like & getrecommendations! Published in 2023 at "Indian Journal of Pharmacology"
DOI: 10.4103/ijp.ijp_706_22
Abstract: OBJECTIVE: Human cytochrome p450 enzymes play an important role in the metabolism of various substances. The CYP2C subfamily consists of various important drug-metabolizing enzymes such as CYP2C9 and CYP2C19. The objectives of the study include… read more here.
Keywords: clopidogrel efficacy; cyp2c19; cyp2c19 variant; cyp2c9 cyp2c19 ... See more keywords