Effect of chronic unpredicted mild stress-induced depression on clopidogrel pharmacokinetics in rats
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DOI: 10.7717/peerj.14111
Abstract: Background Clopidogrel is widely used to prevent and treat cardiovascular atherosclerosis and thrombosis. However, disturbance in the expression and activity of liver cytochrome metabolic enzymes significantly changes clopidogrel efficacy. Therefore, the effect of chronic unpredictable… read more here.
Keywords: effect chronic; clopidogrel pharmacokinetics; induced depression; depression ... See more keywords